3589-06-8

Basic information

• Product Name: 5H-Tetrazol-5-one, 1-(4-chlorophenyl)-1,2-dihydro-
• CAS NO: 3589-06-8
• Molecular Formula: C7H5ClN4O
• Molecular Weight: 196.596
• Mol File: 3589-06-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 5H-Tetrazol-5-one, 1-(4-chlorophenyl)-1,2-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Tetrazol-5-one, 1-(4-chlorophenyl)-1,2-dihydro-(3589-06-8)
• EPA Substance Registry System: 5H-Tetrazol-5-one, 1-(4-chlorophenyl)-1,2-dihydro-(3589-06-8)

Safety Data

• Hazardous Substances Data: 3589-06-8(Hazardous Substances Data)

Usage

Description

It is a dihydro derivative of 5H-tetrazol-5-one with a 4-chlorophenyl group.

Applications

Primarily studied for potential pharmaceutical applications, especially in drug development. Also, it could be used in organic compound synthesis.

Handling Precautions

Due to possible hazardous properties, careful handling in accordance with safety guidelines and regulations is essential.

Upstream product

• 104-12-1 p-chlorphenylisocyanate 
• 122-01-0 4-chloro-benzoyl chloride 
• 109-99-9 tetrahydrofuran 
• 7446-70-0 aluminium trichloride 

Downstream Products

• 54246-60-5 1-(4-chlorophenyl)-4-methyl-1H-tetrazol-5(4H)-one 
• 155431-82-6 1-(4-chlorophenyl)-4-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-5(1H,4H)-tetrazolone 
• 928343-00-4 C₁₀H₇ClN₆OS₂ 

Relevant articles and documents

GPR139 RECEPTOR MODULATORS

Compounds are provided that modulate the GPR139 receptor, compositions containing the same, and to methods of their preparation and use for treatment of a malcondition wherein modulation of the GPR139 receptor is medically indicated or beneficial. Such compounds have the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein R1, R4, R5, R9, R10, Q6, Q7, and Q12 are as defined herein.

Silicon-mediated direct conversion of acyl chlorides to carbamoyl azides or/and tetrazolinones under mild conditions

A simple and mild one-pot procedure for the synthesis of carbamoyl azides from acyl chlorides utilizing a combination of tetrachlorosilane and sodium azide in acetonitrile at ambient temperature is reported. Under gentle heating 1-aryltetrazolin-5- ones were also obtained in one-pot process presumably via a [3 + 2] cycloaddition step.

Design and synthesis of diheterocyclic compounds containing tetrazolinone and 1,2,4-triazole

(Chemical Equation Presented) A novel series of 1-(4-chlorophenyl)-4-{[5- (alkylthio)-4-phenyl-4H-1,2,4-triazol-3-yl]methyl}-1,4-dihydro-5H-tetrazol-5- ones 6a-y were synthesized in good to excellent yields and their structures were identified by 1/