3594-91-0

Basic information

• Product Name: [2-[2-(hydroxymethyl)-6-methyl-phenyl]-3-methyl-phenyl]methanol
• Synonyms: [2-[2-(hydroxymethyl)-6-methyl-phenyl]-3-methyl-phenyl]methanol
• CAS NO: 3594-91-0
• Molecular Formula: C₁₆H₁₈O₂
• Molecular Weight: 0
• Mol File: 3594-91-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 419 °C at 760 mmHg
• Flash Point: 199.3 °C
• Appearance: /
• Density: 1.127 g/cm³
• CAS DataBase Reference: [2-[2-(hydroxymethyl)-6-methyl-phenyl]-3-methyl-phenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [2-[2-(hydroxymethyl)-6-methyl-phenyl]-3-methyl-phenyl]methanol(3594-91-0)
• EPA Substance Registry System: [2-[2-(hydroxymethyl)-6-methyl-phenyl]-3-methyl-phenyl]methanol(3594-91-0)

Safety Data

• Hazardous Substances Data: 3594-91-0(Hazardous Substances Data)

Usage

General Description

The chemical compound [2-[2-(hydroxymethyl)-6-methyl-phenyl]-3-methyl-phenyl]methanol is a synthetic organic compound that belongs to the class of phenols. It is classified as a derivative of benzyl alcohol, containing a benzyl group substituted with hydroxy and methyl groups. [2-[2-(hydroxymethyl)-6-methyl-phenyl]-3-methyl-phenyl]methanol is commonly used in the production of various pharmaceuticals, dyes, and fragrances due to its aromatic properties and functional groups. It is also used as an intermediate in organic synthesis and chemical research. Additionally, its structure makes it a useful building block for creating new compounds with potential applications in the pharmaceutical and chemical industries.

Upstream product

• 57024-47-2 6,6'-dimethyl-1,1'-biphenyl-2,2'-dicarboxylic acid 
• 1127-59-9 7-methyl-1H-indole-2,3-dione 
• 199440-13-6 2-bromo-1-({2-[(2-bromo-3-methylbenzyl)oxy]-1,2-diphenylethoxy}methyl)-3-methylbenzene 
• 66790-58-7 2-bromo-1-(bromomethyl)-3-methylbenzene 
• 99-04-7 m-Toluic acid 
• 103441-60-7 methyl 2-iodo-3-methylbenzoate 
• 108078-14-4 2-iodo-3-methylbenzoic acid 
• 4389-45-1 3-methylantranilic acid 
• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 93878-26-3 dimethyl 6,6'-dimethylbiphenyl-2-2'-dicarboxylate 
• 71871-12-0 dimethyl (+/-)-6,6'-diethyldiphenate 

Downstream Products

• 32750-01-9 6,6'-dimethyl-2,2'-biphenyldiol 

Relevant articles and documents

New biphenyl iminium salt catalysts for highly enantioselective asymmetric epoxidation: Role of additional substitution and dihedral angle

New biaryl iminium salt catalysts for enantioselective alkene epoxidation containing additional substitution in the heterocyclic ring are reported. The effects upon conformation and enantioselectivity of this additional substitution, and the influence of dihedral angle in these systems, has been investigated using a synthetic approach supported by density functional theory. Enantioselectivities of up to 97% ee were observed.

New, axially chiral, bimetallic catalysts for asymmetric alkylation of aldehydes with diethylzinc

Axially chiral bis(salicylidene)ethylenediamine (H2salen)-type ligands 3 (cf. Schemes 1 and 3) are efficient ligands for the enantioselective addition of diethylzinc to aldehydes. There is ample evidence that an active bimetallic catalyst forms an effective chiral pocket (see Fig. 2); of a series of first-row transition-metal complexes with these ligands, the most stereoselective were the Co(II) complexes (see Fig. 1). Best ee values as well as the fastest rates (see Tables 2 and 3) were obtained with these Co(II) complexes when an EtO substituent was present at C(3) of the salicylaldehyde residues of ligand 3 (R1 = EtO), i.e., complex [Co(II)(3'h)] produce d up to 93% ee with aromatic aldehydes and 78% ee for aliphatic aldehydes (see Table 4).