360-70-3

Basic information

• Product Name: Nandrolone Decanoate
• Synonyms: DECANOIC ACID 13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHE;DECADURABOLIN;4-ESTREN-17BETA-OL-3-ONE 17-DECANOATE;4-ESTREN-17-BETA-OL-3-ONE DECANOATE;19-nortestoterone decanoate;19-NORTESTOSTERONE 17-DECANOATE;19-NORTESTOSTERONE DECANOATE;17BETA-HYDROXY-19-NOR-4-ANDROSTEN-3-ONE 17-DECANOATE
• CAS NO: 360-70-3
• Molecular Formula: C₂₈H₄₄O₃
• Molecular Weight: 428.65
• EINECS: 206-639-3
• Product Categories: Steroids;Steroid and Hormone;Finished Steroid and Hormone;API;nandrolone series;Inhibitors;Nandrolone?Decanoate ada@tuskwei.com whatsapp;8618031153937
• Mol File: 360-70-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 33-37°C
• Boiling Point: 483.46°C (rough estimate)
• Flash Point: 226.8 °C
• Appearance: white to light yellow/powder
• Density: 1.0406 (rough estimate)
• Vapor Pressure: 1.3E-11mmHg at 25°C
• Refractive Index: 1.4700 (estimate)
• Storage Temp.: 2-8°C
• Solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL
• Water Solubility: 664ug/L(37 oC)
• CAS DataBase Reference: Nandrolone Decanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Nandrolone Decanoate(360-70-3)
• EPA Substance Registry System: Nandrolone Decanoate(360-70-3)

Safety Data

• Hazard Codes: Xn
• Statements: 40
• Safety Statements: 22-36
• WGK Germany: 3
• RTECS: KG7967000
• Hazardous Substances Data: 360-70-3(Hazardous Substances Data)

Usage

Description

Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis. The process for creating esters of [nandrolone] was patented in Spain in 1959 and in 1960, it was described as having a long duration of action and strong anabolic effect compared to nandrolone and other esters. Nandrolone decanoate was granted FDA approval on 5 October 1962.

Chemical Properties

White or almost white, crystalline powder.

Originator

Deca-Durabolin,Organon,US,1962

Uses

Nandrolone Decanoate is an anabolic steroid. Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women. Nandrolone Decanoate is also used for some aplastic anemias. Control led Substance.

Manufacturing Process

1 gram of 19-nortestosterone is dissolved in 3 ml of dry pyridine, after which the resulting solution is cooled to -20°C. A solution of 1.0 gram of decanoic acid chloride in 3 ml of dry benzene is added to the cooled solution. The mixture is maintained at -15°C for 16 hours and then poured into ice water. The aqueous liquid is extracted with benzene, the benzene solution is washed with respectively 1 N sodium hydroxide solution, 2 N hydrochloric acid and with water until neutral reaction.Then the solution is dried on sodium sulfate, filtered, and evaporated to dryness. The residue, 1.63 grams is dissolved in hexane, this solution is filtered over 30 grams of neutral aluminum oxide, and evaporated to dryness. On paper chromatographic investigation it turned out that the obtained 19- nortestosterone 17-decanoate which at room temperature is an oil consists of a single compound, according to US Patent 2,998,423.

Brand name

Durabolin (Organon);Abolon;Activin;Anabolin la 100;Anador;Anadur;Analone-50;Androlone d 100;Androlone d 50;Decabolin;Deca-durabolin decanoate;Deca-noralone;Docabolin;Fherbolico;Fortabolin;Hybolin-decanoate;Iebolan;Kabolin;Keratyl;Methybol-depot;Nandrolone decanoate;Nordecon;Stenabolin;Sterobolin;Turinabol-depot.

Therapeutic Function

Anabolic

World Health Organization (WHO)

Nandrolone decanoate, an anabolic steroid, was introduced in 1962. In 1982, low dosage preparations were prohibited in Bangladesh due to inadmissible promotion of products containing anabolic steroids for malnourished children. Higher dosage preparations of nandrolone decanoate remain available in many countries, including Bangladesh, for several highly specific but limited indications that apply to patients with chronic debilitating and emaciating diseases, particularly associated with neoplasia and some types of aplastic anaemia.

General Description

Nandrolone decanoate,17β-hydroxyestr-4-en-3-one 17-decanoate, has been used inthe management of certain anemias, but the availability oferythropoietin has greatly reduced this use.

Safety Profile

Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.

Veterinary Drugs and Treatments

The principle use of nandrolone in veterinary medicine has been to stimulate erythropoiesis in patients with certain anemias (e.g., secondary to renal failure, aplastic anemias). It has also been suggested for use as an appetite stimulant.

InChI:InChI=1/C28H44O3/c1-3-4-5-6-7-8-9-10-27(30)31-26-16-15-25-24-13-11-20-19-21(29)12-14-22(20)23(24)17-18-28(25,26)2/h19,22-26H,3-18H2,1-2H3/t22-,23+,24+,25-,26-,28-/m0/s1