3600-61-1

Basic information

• Product Name: 4,4'-dihydroxychalcone
• Synonyms: 4,4'-dihydroxychalcone
• CAS NO: 3600-61-1
• Molecular Formula: C₁₅H₁₂O₃
• Molecular Weight: 240.25
• Mol File: 3600-61-1.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 469.8 °C at 760 mmHg
• Flash Point: 252 °C
• Appearance: /
• Density: 1.286 g/cm³
• CAS DataBase Reference: 4,4'-dihydroxychalcone(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-dihydroxychalcone(3600-61-1)
• EPA Substance Registry System: 4,4'-dihydroxychalcone(3600-61-1)

Safety Data

• Hazardous Substances Data: 3600-61-1(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 99-93-4 4-Hydroxyacetophenone 
• 2373-89-9 4,4'-dimethoxychalcone 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 457629-77-5 4,4'-bis(tetrahydropyran-2-yloxy)chalcone 
• 109555-07-9 4,4'-diacetoxychalcone 

Downstream Products

• 112163-64-1 4,4'-dinonyloxychalcone 
• 112163-65-2 (E)-1,3-Bis-(4-decyloxy-phenyl)-propenone 
• 1222313-17-8 4-(4'-hydroxyphenyl)-2-(4-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepine 

Relevant articles and documents

Method for efficiently synthesizing 1, 3-bis (4-hydroxyphenyl)-2-propylene-1-ketone

The invention discloses a method for efficiently synthesizing 1, 3-bis (4-hydroxyphenyl)-2-propene-1-ketone, and belongs to the field of organic chemical synthesis. According to the method, a Claisen-Schmidt reaction is carried out, p-hydroxybenzaldehyde

Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia

Based on hit-likeness and chemical diversity, a number of chalcones and chalcone-mimetic compounds were selected as putative Notch inhibitors. The evaluation of the antiproliferative effect combined with the inhibition of Notch1 expression in KOPTK1 cell line identified compound 18, featuring a tetrahydronaphthalene-based scaffold, as a new promising Notch-blocking agent.

BENZOXAZINES WITH PHOTO-CURABLE LINKAGES, THERMOSETS THEREOF, AND PREPARATION OF THE SAME

The subject invention provides benzoxazines with photo-curable linkages, thermosets thereof, and preparation methods of the same. The compounds of the subject invention can be used in manufacture of many kinds of cross-linking polymer material, and the obtained material is improved in terms of many properties, especially high thermal properties. Moreover, the preparation method of the subject invention can precisely synthesize the targeted products by simply steps.