3601-90-9

Basic information

• Product Name: 1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose
• Synonyms: 1-Chloro-2-Deoxy-3,5-Di(O-P-Chlorobenzoyl)-D-Ribofuranose;2-Deoxy-3,5-bis-O-(4-chlorobenzoyl)-D-erythro-pent;3,5-O-Bis(4-chlorobenzoyl)-2-deoxy-D-ribofuranosyl;1-Chloro-3,5-Di-(P-Chlorobenzo;1-CHLORO-3,5-DIPARACHLOROBENZOYL-2-DEOXY-D-RIBOSE;1-Chloro-2-deoxy-3,5-bi (O-p-aldylbenzoyl)-D-ribofuranose;1-CHLORO-3,5-DI(4-CHLORBENZOYL)-2-DEOXY-D-RIBOSE;3,5-O-Bis(4-chlorobenzoyl)-2-deoxy-D-ribofuranosyl chloride
• CAS NO: 3601-90-9
• Molecular Formula: C₁₉H₁₅Cl₃O₅
• Molecular Weight: 445.68
• EINECS: 1806241-263-5
• Product Categories: Dextrins、Sugar & Carbohydrates;intermeiates
• Mol File: 3601-90-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 682.3oC at 760mmHg
• Flash Point: 366.4oC
• Appearance: /
• Density: 1.46
• Vapor Pressure: 1.5E-19mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose(3601-90-9)
• EPA Substance Registry System: 1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose(3601-90-9)

Safety Data

• Hazardous Substances Data: 3601-90-9(Hazardous Substances Data)

Usage

General Description

1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose is a chemical compound that contains a deoxyribose sugar molecule with two chlorine atoms and two 4-chlorobenzoyl groups attached to it. 1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose is a derivative of deoxyribose, a key component of DNA, and the presence of the chlorobenzoyl groups makes it potentially useful in pharmaceutical and chemical research applications. It is likely to have a high degree of chemical reactivity and may be used in the synthesis of more complex molecules for various industrial and academic purposes. The compound's specific properties and potential uses should be evaluated in the context of specific research or development projects.

InChI:InChI=1/C19H15Cl3O6/c20-12-5-1-10(2-6-12)15(24)16(25)18(27)19(28,9-14(22)23)17(26)11-3-7-13(21)8-4-11/h1-8,16,18,25,27-28H,9H2/t16?,18-,19-/m1/s1

Upstream product

• 452-51-7 D-2-deoxyribose 
• 122-01-0 4-chloro-benzoyl chloride 
• 80184-05-0 1-chloro-2-deoxy-D-ribofuranose 

Downstream Products

• 132665-69-1 7-<2-deoxy-3,5-di-O-(p-chlorobenzoyl)-β-d-erythropentofuranosyl>-5,6-dimethylpyrrolo<2,3-d>pyrimidin-4-amine 
• 158226-23-4 β-5-(bromoethynyl)-1-<2-'deoxy-3',5'-di-O-(p-chlorobenzoyl)>-uridine 
• 158226-24-5 α-5-(bromoethynyl)-1-<2-'deoxy-3',5'-di-O-(p-chlorobenzoyl)>-uridine 
• 111733-82-5 1-(2'-Desoxy-3',5'-di-O-(p-chlorbenzoyl)-β-D-ribofuranosyl)-2,3-(1H,4H)-chinoxalindion 
• 111733-81-4 1-(2'-Desoxy-3',5'-di-O-(p-chlorbenzoyl)-α-D-ribofuranosyl)-2,3-(1H,4H)-chinoxalindion 
• 357281-99-3 3,5-bis-O-(p-chlorobenzoyl)-2-deoxy-D-ribofuranosyl cyanide 
• 357282-02-1 2-nitrobenzyl 1'-cyano-2'-deoxy-D-ribofuranoside 
• 357282-05-4 α-2-nitrobenzyl 1'-cyano-5'-O-(4-monomethoxytrityl)-2'-deoxy-D-ribofuranoside 
• 357282-03-2 β-2-nitrobenzyl 1'-cyano-5'-O-(4-monomethoxytrityl)-2'-deoxy-D-ribofuranoside 
• 80384-36-7 5-(bromoethynyl)-α-2'-deoxyuridine 
• 80384-36-7 5-(bromoethynyl)-β-2'-deoxyuridine 
• 1000889-58-6 1'-ethynyl-2'-deoxy-D-ribose 
• 1005173-99-8 2-nitrobenzyl 3,5-di-O-(4-chlorobenzoyl)-2-deoxy-β-D-ribofuranoside 
• 1005174-10-6 2-nitrobenzyl 3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranoside 

Relevant articles and documents

Synthesis and DNA incorporation of an ethynyl-bridged cytosine C-nucleoside as guanosine surrogate

(Chemical Equation Presented) As a guanosine mimic that lacks the preference for syn or anti conformation a cytosine C-nucleoside was synthesized connecting the nucleobase at the anomeric center by an ethynyl linker. The key step was a Sonogashira cross coupling of 5-iodocytosine with 1′-ethynyl-2′-deoxyribose. The new C-nucleoside incorporated into G/C-alternating oligonucleotides emerged as guanosine substitute, however, with reduced duplex stability. B-Form DNA was strongly stabilized by the new surrogate even in typically Z-DNA forming sequences and in Z-form inducing environment.

Steric fixation of bromovinyluracil: Synthesis of furo[2,3-d]pyrimidine nucleosides

A new synthetic proccdure for the preparation of 5,6-dihydrofuro[2,3-d]pyrimidin-2(3H)-one (3) and its deoxyriboside 8 is reported. Compound 3 undergoes nucleophilic reactions with various agents to yield 5-substituted uracil derivatives. The dehydro derivative of 3, furo[2,3-d]pyrimidin-2(3H)-one (18) was synthesized by cyclization of BVU 15, which made us develop a reproducible and high yield method for the synthesis of BV(D)U. Starting from 18, the α-deoxyriboside 20 and the β-riboside 22 were prepared.