36034-54-5

Basic information

• Product Name: 4-Methoxyisoquinoline
• Synonyms: 4-Methoxyisoquinoline
• CAS NO: 36034-54-5
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.18
• EINECS: -0
• Mol File: 36034-54-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 295.6±13.0 °C(Predicted)
• Appearance: /
• Density: 1.130
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.04±0.10(Predicted)
• CAS DataBase Reference: 4-Methoxyisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxyisoquinoline(36034-54-5)
• EPA Substance Registry System: 4-Methoxyisoquinoline(36034-54-5)

Safety Data

• Hazardous Substances Data: 36034-54-5(Hazardous Substances Data)

Usage

General Description

4-Methoxyisoquinoline is a chemical compound that belongs to the class of isoquinoline alkaloids. It is a derivative of isoquinoline, and its molecular structure contains a methoxy group on the 4th carbon atom of the isoquinoline ring. 4-Methoxyisoquinoline has been found to exhibit various biological activities, including as an antioxidant and antimicrobial agent. It has also been studied for its potential applications in the pharmaceutical industry, particularly for its ability to inhibit the growth of certain cancer cells and as a potential candidate for the development of new drugs. Additionally, 4-Methoxyisoquinoline has shown potential for its use as a fluorescent probe in analytical chemistry and bioimaging applications.

Upstream product

• 76570-11-1 4--methoxyisoquinoline N--oxide 
• 1532-97-4 4-bromoisoquinoline 
• 865-33-8 potassium methanolate 
• 67-56-1 methanol 

Relevant articles and documents

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Mild and general palladium-catalyzed synthesis of methyl aryl ethers enabled by the use of a palladacycle precatalyst

A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield.

Photochemistry of Methoxy-substituted Quinoline and Isoquinoline N-Oxides

The photochemistry of quinoline 1-oxides and isoquinoline 2-oxides bearing a methoxy-group in the pyridine ring was investigated in protic and aprotic media.The formation of various photoisomers, viz. 3,1-benzoxazepines, 2(1H)-quinolones, N-(2-isocyanobenzyl)formamides, 4(1H)-quinolones, and 3-hydroxyquinolines from the different methoxyquinoline 1-oxides, and 1,3-benzoxazepines and 1(2H)-isoquinolones from the different methoxyisoquinoline 2-oxides, was observed along with deoxygenation and formation of products derived from hydration and decomposition of the primary products.The position of the methoxy-group has an important directing effect on the photoreactions.