3607-17-8

Basic information

• Product Name: (3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
• Synonyms: BROMOPROPYLTRIPHENYLPHOSPHONIUM BROMIDE;(3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE;bromo(3-bromopropyl)triphenylphosphorane;bromo(3-bromopropyl)triphenylphosphorus;3-(bromopropyl)triphenylphosphonium;(3-Bromopropyl)triphenylphosphonium bromide, 98 %;NSC 84074;(3-Bromopropyl)triphenylphosphonium bromide 98%
• CAS NO: 3607-17-8
• Molecular Formula: Br*C₂₁H₂₁BrP
• Molecular Weight: 464.17
• EINECS: 222-770-9
• Product Categories: Phosphonium Compounds;Synthetic Organic Chemistry;Wittig & Horner-Emmons Reaction;Wittig Reaction;C-C Bond Formation;Olefination;Wittig Reagents
• Mol File: 3607-17-8.mol
• Article Data: 24

Chemical Properties

• Melting Point: 228-230 °C(lit.)
• Appearance: /solid
• Storage Temp.: Store below +30°C.
• Solubility: Chloroform, Methanol
• Sensitive: Hygroscopic
• BRN: 6422974
• CAS DataBase Reference: (3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE(3607-17-8)
• EPA Substance Registry System: (3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE(3607-17-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-21/22
• Safety Statements: 26-37/39-36/37
• WGK Germany: 3
• Hazardous Substances Data: 3607-17-8(Hazardous Substances Data)

Usage

Chemical Properties

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Uses

Different sources of media describe the Uses of 3607-17-8 differently. You can refer to the following data:
1. (3-Bromopropyl)triphenylphosphonium Bromide is used in rearrangement reactions of cyclic organic molecules and in organic synthesis.
2. Reactant involved in:Synthesis of functionalized polyurethanes using cationic ring-opening polymerization and click chemistrySemipinacol rearrangement and direct arylationOlefination of benzaldehydesC-H activation / cycloisomerizationIntramolecular dehydrobrominationCycloisomerizations of bromodienes and enynes

InChI:InChI=1/C21H21BrP/c22-17-10-18-23(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21/h1-9,11-16H,10,17-18H2/q+1

Upstream product

• 603-35-0 triphenylphosphine 
• 109-64-8 1,3-dibromo-propane 
• 51860-45-8 3-hydroxypropyltriphenylphosphonium bromide 

Downstream Products

• 89229-72-1 cyclopropylidene-2 phenyl-2 dimethoxy-1,1 ethane 
• 881013-16-7 1-(cyclopropylidenemethyl)-2-methylbenzene 
• 918895-35-9 3-triphenylphosphoniopropylthiosulfate 
• 1309565-87-4 1-(cyclopropylidenemethyl)-2-ethynyl-4,5-dimethoxybenzene 
• 1309565-90-9 1-(cyclopropylidenemethyl)-2-ethynyl-4-fluorobenzene 
• 1309565-91-0 2-(cyclopropylidenemethyl)-1-ethynyl-4-fluorobenzene 
• 1309565-89-6 4-chloro-2-(cyclopropylidenemethyl)-1-ethynylbenzene 
• 1309565-94-3 3-(cyclopropylidenemethyl)-2-ethynylpyridine 
• 1309565-88-5 2-(cyclopropylidenemethyl)-1-ethynyl-4-methylbenzene 
• 1309565-85-2 1-(cyclopropylidenemethyl)-2-ethynylbenzene 
• 1309565-92-1 1-(1-cyclopropylideneethyl)-2-ethynylbenzene 
• 1309565-86-3 1-(cyclopropylidenemethyl)-2-ethynyl-4-methoxybenzene 
• 851042-53-0 (2-cyclopropylidenemethylcyclohex-1-enylethyl)trimethylsilane 
• 327155-46-4 tert-butyl-[2-(3-cyclopropylidene-propyl)-phenoxy]-dimethyl-silane 

Relevant articles and documents

Addition of water to arylidenecyclopropanes: A highly efficient method for the preparation of gem-aryl disubstituted homoallylic alcohols

Arylidenecyclopropanes react with water in the presence of a catalytic amount of Cu(OTf)2 to afford the corresponding gem-aryl disubstituted homoallylic alcohols in good to excellent yields.

Strain-Promoted Oxidation of Methylenecyclopropane Derivatives using N-Hydroxyphthalimide and Molecular Oxygen in the Dark

The hydroperoxidation of alkylidenecyclopropanes and other strained alkenes using an N-hydroxylamine and molecular oxygen occurred in the absence of catalyst, initiator, or light. The oxidation reaction proceeds through a radical pathway that is initiated by autoxidation of the alkene substrate. The hydroperoxides were converted to their corresponding alcohols and ketones under mild conditions.

Method for simply preparing high-purity olopatadine hydrochloride intermediate (by machine translation)

The invention provides a simple and convenient method for preparing high-purity [3 - (dimethylamine) propyl] triphenylphosphonium bromide hydrobromide. The obtained (1,3 - bromopropyl) triphenylphosphonium bromide does not need to be separated, and is directly reacted with a dimethylamine aqueous solution in n-heptane so as to obtain [3 - 3 - (dimethylamine) propyl] triphenyl phosphonium bromide hydrobromide crude product which is obtained by hot pulping with anhydrous ethanol to obtain the high-purity [3 - 3 - (dimethylamine) propyl] triphenylphosphonium bromide hydrobromide. (by machine translation)