361391-01-7

Basic information

• Product Name: 4,7-dihydroxy-3-(4-hydroxyphenyl)-2-[4-(2-piperidin-1-ylethoxy)-phenyl]-4-(trifluoromethyl)-2,3-dihydro-4H-1-benzopyran
• Synonyms: 4,7-dihydroxy-3-(4-hydroxyphenyl)-2-[4-(2-piperidin-1-ylethoxy)-phenyl]-4-(trifluoromethyl)-2,3-dihydro-4H-1-benzopyran
• CAS NO: 361391-01-7
• Molecular Weight: 529.556
• Mol File: 361391-01-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,7-dihydroxy-3-(4-hydroxyphenyl)-2-[4-(2-piperidin-1-ylethoxy)-phenyl]-4-(trifluoromethyl)-2,3-dihydro-4H-1-benzopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-dihydroxy-3-(4-hydroxyphenyl)-2-[4-(2-piperidin-1-ylethoxy)-phenyl]-4-(trifluoromethyl)-2,3-dihydro-4H-1-benzopyran(361391-01-7)
• EPA Substance Registry System: 4,7-dihydroxy-3-(4-hydroxyphenyl)-2-[4-(2-piperidin-1-ylethoxy)-phenyl]-4-(trifluoromethyl)-2,3-dihydro-4H-1-benzopyran(361391-01-7)

Safety Data

• Hazardous Substances Data: 361391-01-7(Hazardous Substances Data)

Upstream product

• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 151533-32-3 2-(4''-[2'''-piperidinoethoxy]phenyl)-3-(4'-tetrahydropyranyloxyphenyl)-7-tetrahydropyranyloxy-2,3-dihydro-4H-1-benzopyran-4-one 

Downstream Products

• 361390-51-4 (-)-7-Hydroxy-3-(4-hydroxyphenyl)-2-[4-(2-piperidin-1-ylethoxy)-phenyl]-4-(trifluoromethyl)-2H-1-benzopyran 

Relevant articles and documents

4-fluoroalkyl-2h-benzopyrans anti-estogenic activity

This invention describes the new 4-fluoroalkyl-2H-benzopyrans of general formula I, in which Z is a straight-chain or branched-chain alkyl group with up to 5 carbon atoms that is fluorinated in at least one place, preferably a trifluoromethyl group, and R1, R2, X, Y and n have the meanings that are indicated in the description. The new compounds have at their disposal strong antiestrogenic action. In addition, they can have at their disposal estrogenic action that occurs in a tissue-selective manner. They can be used for the production of pharmaceutical agents, especially for the treatment of estrogen-dependent diseases and tumors and pharmaceutical agents for hormone replacement therapy (HRT) as well as for the prevention and treatment of osteoporosis.