3621-82-7

Basic information

• Product Name: 2,6-Dichlorobenzoxazole
• Synonyms: 2,6-DICHLOROBENZOXAZOLE;2,6-DICHLOROBENZOXAZOLE 99+%;Benzoxazole, 2,6- dichloro-;2,6-Dichlorobenzoxazolel;2,6-dichloro-1,3-benzoxazole;2,6-Dichloro-1,3-benzoxazole 98+%;6-Dichlorobenzoxazole;2,6-dichlorobenzo[d]oxazole
• CAS NO: 3621-82-7
• Molecular Formula: C₇H₃Cl₂NO
• Molecular Weight: 188.01
• EINECS: 222-818-9
• Product Categories: Oxazole&Isoxazole;Pesticide & intermediate
• Mol File: 3621-82-7.mol
• Article Data: 20

Chemical Properties

• Melting Point: 49-51°C
• Boiling Point: 110°C/13mmHg(lit.)
• Flash Point: 100.7 °C
• Appearance: white crystal
• Density: 1.522 g/cm³
• Vapor Pressure: 0.0516mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.96±0.30(Predicted)
• CAS DataBase Reference: 2,6-Dichlorobenzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dichlorobenzoxazole(3621-82-7)
• EPA Substance Registry System: 2,6-Dichlorobenzoxazole(3621-82-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 3621-82-7(Hazardous Substances Data)

Usage

Uses

2,6-Dichlorobenzoxazole is used in the synthesis of 2-(3-(2,6-dichloro-4-(3,3-dichloroallyloxy)phenoxy)propoxy)-5-(trifluoromethyl)benzo[d]oxazole, an insecticide against Spodoptera exigua.

InChI:InChI=1/C7H3Cl2NO/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H

Upstream product

• 22876-20-6 6-chloro-2-mercaptobenzoxazole 
• 22876-20-6 6-chlorobenzo[d]oxazole-2(3H)-thione 
• 19932-84-4 6-chlorobenzo[d]oxazol-2(3H)-one 
• 59-49-4 2-Benzoxazolinone 
• 95-55-6 2-amino-phenol 
• 28443-50-7 2-amino-5-chlorophenol 
• 95-50-1 1,2-dichloro-benzene 

Downstream Products

• 66546-20-1 4-(6-chlorobenzoxazolyloxy)phenoxypropionic acid methyl ester 
• 1334386-05-8 (S)-2-(4-chloro-2-hydroxyphenylamino)-thiazoline-5,5-dimethyl-4-carboxylic acid 
• 1414919-25-7 [bis-(4-methoxy-phenyl)-phenyl-methyl]-{(R)-4-[5-(6-chloro-benzooxazol-2-yl)-2,4-difluoro-phenyl]-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-yl}-amine 
• 1421278-26-3 6-chloro-2-(3,5-dimethylphenyl)benzo[d]oxazole 
• 1421278-31-0 2,6-bis(3,5-dimethylphenyl)benzo[d]oxazole 
• 1421278-27-4 6-chloro-2-(4-ethylphenyl)benzo[d]oxazole 
• 1421278-32-1 2,6-bis(4-ethylphenyl)benzo[d]oxazole 
• 70299-30-8 6-chloro-2-(4-methoxyphenyl)benzo[d]oxazole 
• 1421278-33-2 2,6-bis(4-methoxyphenyl)benzo[d]oxazole 
• 1315571-14-2 ? 6-chloro-2-(3-fluorophenyl)benzo[d]oxazole 
• 1421278-34-3 2,6-bis(3-fluorophenyl)benzo[d]oxazole 
• 955-76-0 6-chloro-2-(4-chlorophenyl)benzo[d]oxazole 
• 1421278-35-4 2,6-bis(4-chlorophenyl)benzo[d]oxazole 

Relevant articles and documents

High-efficiency low-pollution fenoxaprop-p-ethyl production process

The invention discloses a high-efficiency and low-pollution production process of fenoxaprop-p-ethyl. The production process comprises the following specific steps: (1) preparing fenoxaprop-p-ethyl; S1, preparing sulfydryl-6-chlorobenzoxazole; S2, preparing 2,6-dichlorobenzoxazole; and S3, synthesizing the fenoxaprop-p-ethyl. According to the fenoxaprop-p-ethyl, fenoxaprop-p-ethyl is finally synthesized through preparation of sulfydryl-6-chlorobenzoxazole and preparation of 2,6-dichlorobenzoxazole, the technology is simple, operation is convenient, efficiency is high, the speed is high, the production cost is saved, the income is increased, and filter residues generated in the production process can be safely treated through the technology; the waste gas enters a waste gas treatment facility for treatment and is discharged after reaching the standard; and the wastewater is desalted, removed salt is washed and dried by methanol to serve as a byproduct, and evaporated condensate water enters a factory sewage treatment station to be treated, so that the aim of protecting the environment is fulfilled, and the functions of high efficiency and low pollution are achieved.

HMOX1 inducers

The present invention is related to compounds of structure (I) as heme oxygenase 1 (HMOX 1) inducers. The present invention is also related a method of controlling the activity or the amount, or both the activity and the amount, of heme-oxygenase 1 in a mammalian subject. The definitions of the variables are provided herein.

Synthesis method of 2,6-dichlorobenzooxazole

The invention relates to the field of organic synthesis, and particularly relates to a synthesis method of 2,6-dichlorobenzooxazole. The synthesis method comprises the following steps: adding benzoxazolone and phosphorus oxychloride in a reaction container, carrying out dissolving by stirring, then adding a chlorination reagent, carrying out a chlorination reaction to obtain the 6-dichlorobenzooxazole, adding a certain amount of a catalyst, carrying out heating for reflux, carrying out a reaction for 6-12 hours, removing the solvent after the reaction is ended, and carrying out reduced pressure distillation to obtain the product 2,6-dichlorobenzooxazole. According to the preparation method of the 2,6-dichlorobenzooxazole, the route is short, the yield is high, operation is simple and convenient, three wastes (waste gas, waste water and industrial residue) generated in a reaction process are few, and the method is suitable for large-scale industrial production. In addition, the phosphorus oxychloride is used for replacing virulent phosgene, diphosgene, solid phosgene or phosphorus pentachloride, the safety coefficient during production is improved, and environment friendliness is achieved.