3623-23-2

Basic information

• Product Name: Benzene, 1-broMo-4-nitroso-
• Synonyms: Benzene, 1-broMo-4-nitroso-
• CAS NO: 3623-23-2
• Molecular Formula: C₆H₄BrNO
• Molecular Weight: 186.00606
• Mol File: 3623-23-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 236°C at 760 mmHg
• Flash Point: 96.6°C
• Appearance: /
• Density: 1.61g/cm³
• Vapor Pressure: 0.0742mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: Benzene, 1-broMo-4-nitroso-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-broMo-4-nitroso-(3623-23-2)
• EPA Substance Registry System: Benzene, 1-broMo-4-nitroso-(3623-23-2)

Safety Data

• Hazardous Substances Data: 3623-23-2(Hazardous Substances Data)

Usage

General Description

Benzene, 1-brom-4-nitroso is a chemical compound composed of a benzene ring with a bromine atom and a nitroso group attached to it. It is primarily used in laboratory research and industrial manufacturing processes. This chemical compound is known to have potential hazardous effects on human health and the environment. It is classified as a hazardous substance by several regulatory agencies due to its carcinogenic and toxic properties. Exposure to benzene, 1-brom-4-nitroso can lead to harmful effects on the respiratory system, skin irritation, and damage to the central nervous system. Proper handling and storage procedures are recommended to minimize the risk of exposure and potential harm from this chemical compound.

InChI:InChI=1/C6H4BrNO/c7-5-1-3-6(8-9)4-2-5/h1-4H

Upstream product

• 10468-46-9 N-(4-bromophenyl)hydroxylamine 
• 542-11-0 aniline hydrobromide 
• 6999-03-7 1-bromo-4-(trimethylsilyl)benzene 
• 374564-35-9 potassium 4-bromophenyltrifluoroborate 
• 57574-08-0 p-bromonitrosobenzene dimer 
• 2101-88-4 1-azido-4-bromobenzene 
• 106-40-1 4-bromo-aniline 
• 5467-74-3 4-Bromophenylboronic acid 
• 57574-08-0 4,4'-dibromoazobenzene N,N'-dioxide 
• 763910-59-4 N-(4-bromo-phenyl)-N-nitroso-hydroxylamine 
• 7647-01-0 hydrogenchloride 
• 56-23-5 tetrachloromethane 
• 10035-10-6 hydrogen bromide 
• 7726-95-6 bromine 

Downstream Products

• 31054-09-8 (4-bromo-phenyl)-(2-phenyl-indol-3-ylidene)-amine 
• 105971-14-0 (4-bromo-phenyl)-(3-nitro-phenyl)-diazene 
• 30121-41-6 [2-(4-bromo-phenyl)-4,4-diphenyl-[1,2]oxazetidin-3-ylidene]-p-tolyl-amine 
• 30121-40-5 (4-bromo-phenyl)-[2-(4-bromo-phenyl)-4,4-diphenyl-[1,2]oxazetidin-3-ylidene]-amine 
• 96018-73-4 N-(4-Bromo-phenyl)-N-hydroxy-formamide 
• 118290-25-8 4-Brom-4'-phenylazobenzol 
• 67274-48-0 N-acetyl-N-(4-bromophenyl)hydroxylamine 
• 78677-67-5 C₁₉H₁₅BrN₂O₃ 
• 78677-67-5 C₁₉H₁₅BrN₂O₃ 
• 54470-19-8 5-bromo-3-phenyl-1H-indole 
• 108009-19-4 O-acetyl-N-(4-nitrobenzoyl)-N-(4-bromophenyl)hydroxylamine 
• 1215-42-5 1,2-bis(4-bromophenyl)diazene oxide 
• 82461-71-0 O-benzoyl-N-(4-nitrobenzoyl)-N-(4-bromophenyl)hydroxylamine 
• 35021-82-0 N-(4-bromophenyl)benzohydroxamic acid 

Relevant articles and documents

Solid-state reaction mechanisms in monomer-dimer interconversions of p-bromonitrosobenzene. Single-crystal-to-single-crystal photodissociation and formation of new non-van der Waals close contacts

Thermal and photochemical reactions and the phase transition mechanisms of solid-state monomer-dimer interconversions of p-bromonitrosobenzene were studied on the basis of kinetics data and single-crystal-to-single-crystal transformations. From the crystal structure and packing of p- bromobenzeneazodioxide and the previously determined structure of the freshly sublimed monomer, we have explained both consecutive steps in thermal dimerization. While the first reaction (formation of the metastable dimer) with first-order kinetics affords diminishing of the (2 2 0) critical crystal plane that intersects atoms of the nitroso groups, the second phase transformation step includes four critical planes, which show sigmoid kinetics. In the new phase growth, these crystal planes developed in two (Cartesian) dimensions as vectors perpendicular to ab and ac planes, which is in agreement with the dimensionality previously determined on the basis of the Avrami-Erofeyev analysis (with m = 2.01). Photochromic dissociation of the azodioxide at 100 K was followed by structure determination of the single-crystal-to-single-crystal transformation. A new metastable monomer was discovered, in which, despite bond breaking, the nitrogen atoms of the neighboring monomers remained very close to each other (2.30 A), i.e., 23.3% closer than is the sum of two N-atom van der Waals radii. Such an extraordinary close contact was also observed between N and O atoms. This tight packing can explain why the return to dimerization after the low temperature photodissociation occurs so rapidly at a temperature as low as 170 K.

Synthesis of Di(hetero)arylamines from Nitrosoarenes and Boronic Acids: A General, Mild, and Transition-Metal-Free Coupling

The synthesis of di(hetero)arylamines by a transition-metal-free cross-coupling between nitrosoarenes and boronic acids is reported. The procedure is experimentally simple, fast, mild, and scalable and has a wide functional group tolerance, including carbonyls, nitro, halogens, free OH and NH groups. It also permits the synthesis of sterically hindered compounds.

Para-Selective Halogenation of Nitrosoarenes with Copper(II) Halides

The para-selective direct bromination and chlorination of nitrosoarenes with copper(II) bromide and chloride is reported. Under mild reaction conditions, a range of halogenated arylnitroso compounds are obtained in moderate to good yields with high regioselectivity. Additionally, the versatility of the method is demonstrated by the development of a one-pot procedure to obtain the corresponding para-halogenated aniline- and nitrobenzene derivatives.