3626-00-4

Basic information

• Product Name: 2,2',2'',2'''-(Ethylenebisnitrilo)tetrakis(acetic acid ethyl) ester
• Synonyms: (Ethylenedinitrilo)tetraacetic acid tetraethyl ester;2,2',2'',2'''-(Ethylenebisnitrilo)tetrakis(acetic acid ethyl) ester;EthylenediaMine-N,N,N',N'-tetraacetic Acid Tetraethyl Ester;N,N'-1,2-Ethanediylbis[N-(2-ethoxy-2-oxoethyl)-glycine 1,1'-Diethyl Ester;N,N'-1,2-Ethanediylbis[N-(2-ethoxy-2-oxoethyl)-glycine Diethyl Ester;NSC 93979
• CAS NO: 3626-00-4
• Molecular Formula: C18H32N2O8
• Molecular Weight: 404.46
• Product Categories: Amino Acids & Derivatives, Chelating Agents & Ligands
• Mol File: 3626-00-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 30-32 °C
• Boiling Point: 195-196 °C(Press: 3 Torr)
• Appearance: /
• Density: 1.142±0.06 g/cm3(Predicted)
• PKA: 3.81±0.50(Predicted)
• CAS DataBase Reference: 2,2',2'',2'''-(Ethylenebisnitrilo)tetrakis(acetic acid ethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2',2'',2'''-(Ethylenebisnitrilo)tetrakis(acetic acid ethyl) ester(3626-00-4)
• EPA Substance Registry System: 2,2',2'',2'''-(Ethylenebisnitrilo)tetrakis(acetic acid ethyl) ester(3626-00-4)

Safety Data

• Hazardous Substances Data: 3626-00-4(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Liquid

Uses

Ethylenediamine-N,N,N’,N’-tetraacetic Acid (E917745) derivative. Chelating agent.

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 107-15-3 ethylenediamine 
• 60-00-4 ethylenediaminetetraacetic acid 
• 75-09-2 dichloromethane 
• 64-17-5 ethanol 

Downstream Products

• 90359-20-9 {[2-(bis-ethoxycarbonylmethyl-amino)-ethyl]-ethoxycarbonylmethyl-amino}-acetic acid 

Relevant articles and documents

Design and synthesis of the G-quadruplex-specific cleaving reagent perylene-EDTA·iron(II) [16]

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Synthesis of monomeric acridine derived nucleic acid intercalators

A series of antiviral compounds consisting of an intercalating acridine derived part, a spacer region and a reactive EDTA-derived conjugate was synthesized in an easy sequence. In the presence of ascorbate a reduction of the phage-titer of MS2 phages by several logarithmic decades was achieved.

Synthesis of pathogen inactivating nucleic acid intercalators

A series of antiviral compounds consisting of an intercalating acridine derived part, a spacer region and a reactive EDTA-derived conjugate was synthesized in an easy sequence starting from 1,ω-alkyldiamines. As shown in model screenings, in the presence of ascorbic acid the Fe-complexes of these compounds reduced the phage-titer of MS2-phages by several logarithmic decades.