3626-97-9

Basic information

• Product Name: (2Z)-2-chloro-3-(4-nitrophenyl)prop-2-enal
• Synonyms: 2-Chloro-3-(4-nitrophenyl)-2-propenal
• CAS NO: 3626-97-9
• Molecular Formula: C₉H₆ClNO₃
• Molecular Weight: 211.6018
• Mol File: 3626-97-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 341.9°C at 760 mmHg
• Flash Point: 160.6°C
• Density: 1.403g/cm³
• Vapor Pressure: 7.82E-05mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: (2Z)-2-chloro-3-(4-nitrophenyl)prop-2-enal(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-2-chloro-3-(4-nitrophenyl)prop-2-enal(3626-97-9)
• EPA Substance Registry System: (2Z)-2-chloro-3-(4-nitrophenyl)prop-2-enal(3626-97-9)

Safety Data

• Hazardous Substances Data: 3626-97-9(Hazardous Substances Data)

Upstream product

• 515-83-3 chloral ethyl hemiacetal 
• 555-16-8 4-nitrobenzaldehdye 
• 104-55-2 3-phenyl-propenal 
• 20473-36-3 2,3-dichloro-3-phenyl-propionaldehyde 

Downstream Products

• 60951-73-7 α-chloro-4-nitro-cinnamic acid 
• 130366-31-3 (1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)-acetic acid [(Z)-2-chloro-3-(4-nitro-phenyl)-prop-2-en-(E)-ylidene]-hydrazide 
• 91456-77-8 6-{[(Z)-2-Chloro-3-(4-nitro-phenyl)-prop-2-en-(E)-ylidene]-hydrazonomethyl}-1,8-dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione 
• 74073-78-2 3,3'-butane-1,4-diyl-bis-thiazolidine-2,4-dione 4,4'-bis-{[2-chloro-3-(4-nitro-phenyl)-allylidene]-hydrazone} 

Relevant articles and documents

Convenient preparation of (Z)-α-halo-α,β-unsaturated aldehydes: synthesis of a Laurencia flexilis toxin

The CrCl2-mediated two-carbon halo-homologation of aryl, alkenyl, and aliphatic aldehydes with chloral ethyl hemiacetal or bromal affords (Z)-α-chloro- and (Z)-α-bromo-α,β-unsaturated aldehydes, respectively, in good to excellent yields and high stereoselectivity. The utility of this methodology was illustrated by a synthesis of 2-chloropentadec-2(Z)-enal, a toxin isolated from the marine red alga Laurencia flexilis.

Synthesis of n-nitro-a-chlorcinnamate aldehyde -- corynal

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