36265-54-0 Usage
General Description
1,2-BIS-(4-METHOXY-PHENYL)-ETHYLAMINE, also known as 1,2-bis(4-methoxyphenyl)ethanamine, is a chemical compound with the molecular formula C17H21NO2. It is a derivative of phenethylamine and belongs to the class of amines. 1,2-BIS-(4-METHOXY-PHENYL)-ETHYLAMINE is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. It has been studied for its potential pharmacological activities, including its role as a selective serotonin reuptake inhibitor and its potential as a novel therapeutic agent. Further research is being conducted to explore its pharmacological properties and potential applications in the medical and pharmaceutical fields.
Check Digit Verification of cas no
The CAS Registry Mumber 36265-54-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,2,6 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 36265-54:
(7*3)+(6*6)+(5*2)+(4*6)+(3*5)+(2*5)+(1*4)=120
120 % 10 = 0
So 36265-54-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H19NO2/c1-18-14-7-3-12(4-8-14)11-16(17)13-5-9-15(19-2)10-6-13/h3-10,16H,11,17H2,1-2H3
36265-54-0Relevant articles and documents
Substituted (1,2-Diarylethyl)amide Acyl-CoA:Cholesterol Acyltransferase Inhibitors: Effect of Polar Groups on in Vitro and in Vivo Activity
Clader, John W.,Berger, Joel G.,Burrier, Robert E.,Davis, Harry R.,Domalski, Martin,et al.
, p. 1600 - 1607 (2007/10/02)
Substituted (1,2-diarylethyl)amides have been prepared and evaluated for their ability to inhibit microsomal acyl-CoA:cholesterol acyltransferase activity in vitro and to lower hepatic cholesteryl ester content in vivo in a cholesterol-fed hamster.Simple unsubstituted (diarylethyl)amides were potent inhibitors in vitro but showed poor activity in vivo.Introduction of polar groups at specific locations on the diarylethylamine moiety decreased in vitro activity but increased in vivo activity.Both effects were highly structure dependent, suggesting specific interactions which were mediating activity in each model.Optimization of these opposing effects led to compounds which were potent in both models.
