362670-07-3

Basic information

• Product Name: (2-AMINO-5-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: N2-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine;N2-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine;(2-AMINO-5-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER;tert-butyl (2-aMino-5-fluorophenyl)carbaMate
• CAS NO: 362670-07-3
• Molecular Formula: C₁₁H₁₅FN₂O₂
• Molecular Weight: 226.25
• Mol File: 362670-07-3.mol
• Article Data: 13

Chemical Properties

• Melting Point: 100.0 to 104.0 °C
• Appearance: /
• CAS DataBase Reference: (2-AMINO-5-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-5-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(362670-07-3)
• EPA Substance Registry System: (2-AMINO-5-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(362670-07-3)

Safety Data

• Hazardous Substances Data: 362670-07-3(Hazardous Substances Data)

Usage

General Description

(2-Amino-5-Fluoro-Phenyl)-Carbamic Acid Tert-Butyl Ester, also known as Tert-Butyl (2-amino-5-fluorophenyl)carbamate, is a chemical compound with the molecular formula C11H15FN2O2. It is a tert-butyl ester derivative of (2-amino-5-fluorophenyl)carbamic acid and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. (2-AMINO-5-FLUORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER has several potential applications in the field of medicinal chemistry and drug discovery due to its ability to modify the activity or stability of target proteins. It is important to handle and store this chemical with care, as it may pose health and environmental hazards if not properly managed.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 2369-11-1 5-fluoro-2-nitroaniline 
• 362670-06-2 (5-fluoro-2-nitrophenyl)carbamic acid tert-butyl ester 
• 367-31-7 4-fluoro-1,2-phenylenediamine 

Downstream Products

• 1360871-23-3 3-ethyl-7-fluoro-4-(4-methoxyphenyl)imidazo[1,5-a]quinoxaline 
• 862815-01-8 (2-ethylamino-5-fluoro-phenyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

HDAC DEGRADER

The disclosure provides compounds of formula (I). The compounds may be used to degrade the Histone Deacetylase (HDAC) family of enzymes, particularly HDAC1, 2 and 3 that exist in corepressor complexes. Accordingly, the compounds may

Phthalazine derivative, preparation method and applications thereof

The invention discloses a phthalazine derivative, a preparation method and applications thereof, and belongs to the field of medicinal chemistry, wherein the phthalazine derivative prepared by the invention is a good PARP and HDAC double-target inhibitor.

1,3-dioxo-isoindoline benzamide compound and application thereof

The invention belongs to the technical field of diabetes treatment medicines and in particular relates to an N-(2-aminophenyl)-3-(1,3-dioxo-isoindoline-2-yl) benzamide compound, and a preparation andapplication thereof in preparing diabetes treatment medicines. The compound has a formula (1) shown in the description, in the formula, R is selected from hydrogen, fluorine, chlorine, bromine, methyl, ethyl, propyl, isopropyl, n-butyl, sec-butyl, isobutyl and tert-butyl, and X is selected from hydrogen or fluorine. The N-(2-aminophenyl)-3-(1,3-dioxo-isoindoline-2-yl) benzamide compound has a remarkable function of protecting pancreatic beta cells, and can be adopted to prepare novel diabetes treatment medicines.