36340-49-5

Basic information

• Product Name: (3E)-4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)but-3-en-2-one
• Synonyms: 3-buten-2-one, 4-(2,2,6-trimethyl-7-oxabicyclo(4.1.0)hept-1-yl)-; 3-Buten-2-one, 4-(2,2,6-trimethyl-7-oxabicyclo(4.1.0)hept-1-yl)-, (E)-; 3-buten-2-one, 4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)-; 4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one; 4-(2,2,6-Trimethyl-7-oxabicyclo(4.1.0)hept-1-yl)-3-buten-2-one
• CAS NO: 36340-49-5
• Molecular Formula: C₁₃H₂₀O₂
• Molecular Weight: 208.2967
• Mol File: 36340-49-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 275.1°C at 760 mmHg
• Flash Point: 103.7°C
• Density: 1.075g/cm³
• Vapor Pressure: 0.0052mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: (3E)-4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)but-3-en-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3E)-4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)but-3-en-2-one(36340-49-5)
• EPA Substance Registry System: (3E)-4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)but-3-en-2-one(36340-49-5)

Safety Data

• Hazardous Substances Data: 36340-49-5(Hazardous Substances Data)

Upstream product

• 79-77-6 (E)-β-ionone 
• 7235-40-7 beta-carotene 
• 1107-26-2 trans-β-apo-8'-carotenal 
• 1638-05-7 12'-apo-β-caroten-12'-al 

Downstream Products

• 50464-95-4 6-methyl-6-(5'-methyl-2'-furyl)heptan-2-one 
• 65912-37-0 (E)-4-(1,2,2-Trimethyl-6-oxo-cyclohexyl)-but-3-en-2-on 
• 107675-07-0 4-(3'-methoxy-3',7',7'-trimethyl-2'-oxa-1'-cycloheptylidene)-2-butanone 
• 107675-04-7 1-(4,4,7a-trimethyl-2,4,5,6,7,7a-hexahydro-benzofuran-2-yl)-ethanone 
• 52588-78-0 6,6-Dimethyl-undeca-3,4-diene-2,10-dione 
• 65868-83-9 6-(3-Acetyl-cycloprop-1-enyl)-6-methylheptan-2-on 
• 65869-11-6 (E)-4-(1-Acetyl-2,2-dimethyl-cyclopentyl)-but-3-en-2-on 
• 107675-08-1 (Z)-6,6-dimethyl-3-undecen-2,5,10-trione 
• 102635-39-2 4-(7',7'-dimethyl-3'-methylidene-2'-oxacycloheptylidene)-2-butanone 
• 65868-84-0 (Z)-4-(1,2,2-Trimethyl-6-oxo-cyclohexyl)but-3-en-2-on 
• 50464-96-5 6,6-dimethylundecane-2,5,10-trione 
• 107675-06-9 (2,2,6-trimethyl-9-oxabicyclo<4.2.1>non-8-en-7-yl) methyl ketone 
• 28494-34-0 4t-(1,2-dihydroxy-2,6,6-trimethyl-cyclohexyl)-but-3-en-2-one 
• 65869-04-7 4-(1,2,2-Trimethyl-6-oxo-cyclohexyl)butan-2-on 

Relevant articles and documents

Organoselenium-catalyzed selectivity-switchable oxidation of β-ionone

Catalyzed by organoselenium compounds, β-ionone was easily oxidized by H2O2 under mild and clean conditions. We were very surprised to find that the reaction selectivity was switchable by the catalyst. To the best of our knowledge, t

Kinetics of β-Carotene Oxidation in the Presence of Highly Active Forms of μ-Carbido Diiron(IV) Tetraphenylporphyrinate

Abstract: The oxidative destruction of β-carotene in the presence of highly oxidized forms of μ-carbido-bis[(5,10,15,20-tetraphenyl-21H,23H-porphyrinato)iron(IV)] (1 → 3) or its analog with axially coordinated imidazole (2 → 4) obtained under the action of tert-butyl hydroperoxide tBuOOH was studied by spectrophotometry. It was found that compound 3 is the oxo form of compound 1 singly oxidized at the macrocyclic ligand (π radical cation) under the action of which β-carotene is oxidized with a rate constant k = 3.3 L2 mol–2 s–1. A?conclusion is drawn that short-lived compound 4 has unique EAS and is capable of oxidizing tBuOOH to form O2, which makes it possible to consider it the model of peroxidase. The value of k for the reaction with the participation of β-carotene and compound 4 (k = 10.3 L2 mol–2 s–1) is three times higher than that with the participation of compound 3. If a new portion of β-carotene is added, the process of its oxidative destruction in the presence of compounds 3 or 4 occurs without additives of the dimeric complex and peroxide. A?possible nature of compound 4 is discussed, as well as the influence of N-base in the coordination sphere of the complex on the nature of active intermediates and the rate of β-carotene decomposition.

MnO2/TBHP: A Versatile and User-Friendly Combination of Reagents for the Oxidation of Allylic and Benzylic Methylene Functional Groups

In the presence of activated MnO2, tert-butyl hydroperoxide (TBHP) in CH2Cl2 is able to oxidize the allylic and benzylic methylene groups of different classes of compounds. I describe a one-pot oxidation protocol based on two sequential steps. In the first step, carried out at low temperature, MnO2 catalyses the oxidation of the methylene group. This is followed by a second step where reaction temperature is increased, allowing MnO2 both to catalyse the decomposition of unreacted TBHP and to oxidize allylic alcohols that could possibly be formed. The proposed oxidation procedure is generally applicable, although its efficiency, regioselectivity, and chemoselectivity are strongly dependent on the structure of the substrate. A simple and user-friendly synthetic procedure for the oxidation of allylic and benzylic methylene groups to the corresponding conjugated carbonyl derivatives is described. The proposed oxidation protocol is based on the combined use of MnO2 and tert-butyl hydroperoxide, and is generally applicable.