364064-17-5

Basic information

• Product Name: 3-(4-FLUOROPHENYL)-5-PYRIDINECARBOXYLIC ACID
• Synonyms: AKOS BAR-1640;3-(4-FLUOROPHENYL)-5-PYRIDINECARBOXYLIC ACID;5-(4-FLUOROPHENYL)NICOTINIC ACID;5-(4-FLUOROPHENYL)PYRIDINE-3-CARBOXYLIC ACID;3,4-9FLUOROPHENYL)-S-PYRIDINE CARBOXYLIC ACID;5-(4-Fluorophenyl)-3-pyridinecarboxylic acid;5-(4-Fluorophenyl)pyridine-3-carboxylic acid for synthesis
• CAS NO: 364064-17-5
• Molecular Formula: C₁₂H₈FNO₂
• Molecular Weight: 217.2
• Product Categories: Heterocyclic Compounds
• Mol File: 364064-17-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 415.7 °C at 760 mmHg
• Flash Point: 205.2 °C
• Appearance: /
• Density: 0.5 g/cm3 (20℃)
• Vapor Pressure: 1.17E-07mmHg at 25°C
• Refractive Index: 1.593
• Storage Temp.: Store below +30°C.
• PKA: 2.08±0.10(Predicted)
• CAS DataBase Reference: 3-(4-FLUOROPHENYL)-5-PYRIDINECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-FLUOROPHENYL)-5-PYRIDINECARBOXYLIC ACID(364064-17-5)
• EPA Substance Registry System: 3-(4-FLUOROPHENYL)-5-PYRIDINECARBOXYLIC ACID(364064-17-5)

Safety Data

• Hazardous Substances Data: 364064-17-5(Hazardous Substances Data)

Usage

General Description

3-(4-fluorophenyl)-5-pyridinecarboxylic acid is a compound with the molecular formula C12H8FNO2. It is a carboxylic acid derivative with a fluorophenyl ring and a pyridine ring. 3-(4-FLUOROPHENYL)-5-PYRIDINECARBOXYLIC ACID is commonly used in the synthesis of pharmaceutical drugs and agrochemicals. It has been studied for its potential therapeutic applications in treating various diseases, including cancer, inflammation, and infections. The presence of the fluorophenyl and pyridine groups in the structure of this compound makes it a valuable building block for the development of new chemical entities with biological activity.

InChI:InChI=1/C12H8FNO2/c13-11-3-1-8(2-4-11)9-5-10(12(15)16)7-14-6-9/h1-7H,(H,15,16)

Upstream product

• 893734-77-5 methyl 5-(4-fluorophenyl)nicotinate 
• 1765-93-1 4-fluoroboronic acid 
• 351529-23-2 (5-bromopyridin-3-yl)methyl acetate 
• 1258269-07-6 ethyl 5-(4-fluorophenyl)nicotinate 
• 20826-04-4 5-bromo-3-pyridinecarboxylic acid 
• 7440-44-0 pyrographite 

Downstream Products

• 381684-96-4 5-(4-fluorophenyl)nicotinaldehyde 
• 85589-65-7 3-(4-fluorophenyl)pyridine 
• 1258268-85-7 C₂₀H₁₇FN₂O 
• 1352786-55-0 1-[5-(4-fluorophenyl)pyridin-3-yl]-3-phenylprop-2-yn-1-one 

Relevant articles and documents

Suzuki coupling reaction for the solid-phase preparation of 5-substituted nicotinic acid derivatives

The application of the Suzuki coupling reaction to the preparation of small combinatorial libraries using 5-bromonicotinic acid as a scaffold onto three different types of solid support (Wang, Rink, and BAL resin) is described. The application of the Suzuki coupling reaction to the preparation of small combinatorial libraries using 5-bromonicotinic acid as a scaffold onto three different types of solid support (Wang, Rink, and BAL resin) is described.

METHOD FOR THE PRODUCTION OF NICOTINALDEHYDES

The invention relates to a method for producing nicotinaldehydes by reducing the corresponding nicotinic acid-morpholine amides.