3645-45-2Relevant articles and documents
NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
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Page/Page column 78-79, (2010/02/12)
Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl-protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human.
CHELATING COMPOUNDS, THEIR COMPLEXES WITH PARAMAGNETIC METALS
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, (2008/06/13)
Compounds able to chelate bi- and trivalent paramagnetic metal ions, their chelated complexes with said metal ions and the physiologically compatible salts thereof, as well as the use thereof as contrast agents in the technique known as “Magnetic Resonanc
N - ( 2 - aryl - propionyl ) - sulfonamides and pharmaceutical preparations containing them
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, (2008/06/13)
The compounds of formula 1, wherein R and R2 are as defined in the disclosure, are useful in the prevention and treatment of tissue damage due to exacerbated recruitment of polymorphonuclear neutrophils (PMN leukocytes) at the inflammatory sites.