36556-33-9

Basic information

• Product Name: 1,3,5-trichloro-2-fluoro-benzene
• Synonyms: 1,3,5-trichloro-2-fluoro-benzene;2,4,6-Trichloro-1-fluorobenzene
• CAS NO: 36556-33-9
• Molecular Formula: C₆H₂Cl₃F
• Molecular Weight: 199.44
• Mol File: 36556-33-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 207.36°C (rough estimate)
• Flash Point: 90.7 °C
• Appearance: /
• Density: 1.54 g/cm³
• Vapor Pressure: 0.177mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1,3,5-trichloro-2-fluoro-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-trichloro-2-fluoro-benzene(36556-33-9)
• EPA Substance Registry System: 1,3,5-trichloro-2-fluoro-benzene(36556-33-9)

Safety Data

• Hazardous Substances Data: 36556-33-9(Hazardous Substances Data)

Usage

General Description

1,3,5-trichloro-2-fluoro-benzene is a chemical compound that consists of a benzene ring with three chlorine atoms and one fluorine atom attached at specific positions. It is a colorless liquid with a strong, sweet odor and is insoluble in water, but soluble in organic solvents. 1,3,5-trichloro-2-fluoro-benzene is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a reagent in organic synthesis and as a solvent in chemical reactions. However, 1,3,5-trichloro-2-fluoro-benzene can be harmful if inhaled or ingested and may cause irritation to the skin and eyes. It is important to handle this chemical with caution and adhere to proper safety protocols when working with it.

InChI:InChI=1/C6H2Cl3F/c7-3-1-4(8)6(10)5(9)2-3/h1-2H

Upstream product

• 18708-70-8 2,4,6-trichloronitrobenzene 
• 634-93-5 2,4,6-trichloroaniline 

Downstream Products

• 94897-81-1 4,5,6-trichloro-2-(2,4,6-trichlorophenoxy)phenol 
• 4780-58-9 2,3,4,6-Tetrachlor-N-methyl-anilin 
• 4877-74-1 2,3,4,6-Tetrachlor-thiophenol 
• 319-95-9 2,3,4,6-Tetrachlorofluorobenzene 
• 4815-62-7 2.4.6-Trichlor-1-fluor-3-nitro-benzol 
• 94888-09-2 4,6-dichloro-2-(2,4,6-trichlorophenoxy)phenol 
• 50903-31-6 5-Chloro-2-(2,4,6-trichloro-phenoxy)-phenol 

Relevant articles and documents

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.

PREPARATION OF AROMATIC FLUORIDES VIA DIAZOTIZATION AND PHOTOCHEMICALLY INDUCED FLUORO-DEDIAZONIATION OF AROMATIC AMINES IN ANHYDROUS HYDROGEN FLUORIDE - ORGANIC BASE SOLUTIONS

Fluoro-dediazoniation of aromatic diazonium ions, produced by the diazotization of the corresponding aromatic amines with NaNO2 in anhydrous hydrogen fluorides (AHF) - organic base solutions, was accelerated photochemically to afford Ar-F efficiently in AHF - organic base solutions in situ.