3659-97-0

Basic information

• Product Name: 1-Methylparabanic acid
• Synonyms: 1-Methyl-2,4,5-imidazolidinetrione;1-Methylimidazolidine-2,4,5-trione;1-Methylparabanic acid;1-Methyl-2,4,5-trioxoimidazolidine;Imidazolidinetrione, methyl-;Methylparabanic acid;N-Methylparabanic acid
• CAS NO: 3659-97-0
• Molecular Formula: C₄H₄N₂O₃
• Molecular Weight: 128.09
• Mol File: 3659-97-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.501g/cm³
• Refractive Index: 1.518
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Methylparabanic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methylparabanic acid(3659-97-0)
• EPA Substance Registry System: 1-Methylparabanic acid(3659-97-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 3659-97-0(Hazardous Substances Data)

Usage

General Description

1-Methylparabanic acid is a chemical compound that is closely related to uric acid and is commonly used in the production of pharmaceuticals and organic compounds. It is a white crystalline solid that is soluble in water and has a molecular formula of C6H4N4O3. 1-Methylparabanic acid is often used as a reagent in the synthesis of various organic compounds and is known for its potent antiseptic and disinfectant properties. Additionally, 1-Methylparabanic acid has been studied for its potential therapeutic applications in the treatment of various diseases and health conditions. Overall, the compound has a wide range of industrial and scientific uses, making it a valuable chemical in various fields.

InChI:InChI=1/C4H4N2O3/c1-6-3(8)2(7)5-4(6)9/h1H3,(H,5,7,9)

Upstream product

• 861071-55-8 N,N'-bis-methylcarbamoyl-oxalamide 
• 64-19-7 acetic acid 
• 79-37-8 oxalyl dichloride 
• 60-29-7 diethyl ether 
• 598-50-5 N-Methylurea 
• 615-77-0 1-methyluracil 
• 19036-49-8 N-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)acetamide 
• 7647-01-0 hydrogenchloride 
• 34356-73-5 2-amino-1-methyl-1H-imidazole-4,5-dione-5-oxime 
• 6972-82-3 5,6-diamino-1-methyluracil 
• 5213-49-0 2,4-dinitro-1H-imidazole 
• 77-78-1 dimethyl sulfate 
• 83-67-0 theobromine / 
• 7697-37-2 nitric acid 

Downstream Products

• 4224-00-4 3-methyl-5,5-diphenyl-imidazolidine-2,4-dione 
• 6843-45-4 1-methylhydantoin 
• 74-89-5 methylamine 
• 144-62-7 oxalic acid 
• 598-50-5 N-Methylurea 
• 956325-62-5 4-({[(methylamino)carbonyl]amino}methyl)benzoic acid 
• 1207374-48-8 1-[(3-phenylimidazolidine-2,4,5-trionyl)methyl]-3-methyl-imidazolidine-2,4,5-trione 
• 1280726-71-7 5-benzylamino-3-methylimidazole-2,4-dione 
• 1280726-73-9 5-(4-methoxybenzyl)amino-3-methylimidazole-2,4-dione 
• 1222979-15-8 1-{2-[2,5-dimethyl-1-(4-trifluoromethoxyphenyl)-1H-pyrrol-3-yl]-2-oxoethyl}-3-methylimidazolidine-2,4,5-trione 
• 110189-06-5 naamidine A 
• 16935-46-9 methyl-phenyl-imidazolidinetrione 
• 14040-79-0 N¹, N²-diphenethyloxalamide 
• 67867-43-0 methyl-phenethyl-imidazolidinetrione 

Relevant articles and documents

Study of the methylation reaction of 2,4-dinitroimidazole and potassium 2,4,5-trinitroimidazol-1-ide with dimethyl sulfate

[Figure not available: see fulltext.] The methylation of 2,4-dinitroimidazole and potassium salt of 2,4,5-trinitroimidazole with dimethyl sulfate was reinvestigated. When the reaction system contained a weak base, the reaction products were 1-methyl-2,4-dinitroimidazole and 1-methyl-2,4,5-trinitroimidazole, respectively. However, in the absence of a base in the reaction system, the products contained oxidation byproducts 1-methylimidazolidine-2,4,5-trione, 1,3-dimethylimidazolidine-2,4,5-trione and recovered starting materials. All products were characterized using FT-IR, NMR, and elemental analysis. The structure of 1-methylimidazolidine-2,4,5-trione and 1,3-dimethylimidazolidine-2,4,5-trione were further confirmed by single crystal X-ray diffraction.

Murexide reaction of caffeine with hydrogen peroxide and hydrochloric acid. II

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2-Amino-1-methyl-1H-imidazole-4,5-dione: Synthesis and the Dimroth Type Rearrangement to Creatone (2-Methyl-amino-1H-imidazole-4,5-dione)

Treatment of creatinine with BOC-ON gave 2-t-butoxycarbonylamino-1-methyl-1,5-dihydro-4H-imidazol-4-one, which was oxidized with mercury(II) acetate to the corresponding 1H-imidazole-4,5-dione.Deprotection of the amino group of this dione afforded the title compound 4, which in turns was shown to undergo a facile, Dimroth-type rearrangement under weakly acidic conditions to give creatone, thus proving 4 to be the key intermediate in the formation of creatone from various starting materials.The equilibria among these compounds are discussed.