366-39-2

Basic information

• Product Name: 2-methylphenyl sulfurofluoridate
• Synonyms: 2-methylphenyl sulfurofluoridate
• CAS NO: 366-39-2
• Molecular Weight: 190.195
• Mol File: 366-39-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-methylphenyl sulfurofluoridate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylphenyl sulfurofluoridate(366-39-2)
• EPA Substance Registry System: 2-methylphenyl sulfurofluoridate(366-39-2)

Safety Data

• Hazardous Substances Data: 366-39-2(Hazardous Substances Data)

Upstream product

• 95-48-7 ortho-cresol 
• 2028-34-4 o-toluene-diazonium chloride 

Downstream Products

• 87-24-1 ethyl 2-methylbenzoate 
• 118-90-1 ortho-methylbenzoic acid 
• 529-20-4 2-methylphenyl aldehyde 
• 3233-56-5 o-cresol sulfate 

Relevant articles and documents

NiCl 2as a Cheap and Efficient Precatalyst for the Coupling of Aryl Fluorosulfonate and Phosphite/Phosphine Oxide

Herein, NiCl 2is employed as a cheap precatalyst in the formation of C(sp 2)-P bond via cross-coupling reaction of phenol derivatives and phosphine oxides/phosphites. This catalytic system allows a variety of phenols with diverse functional groups to transform into phosphates with good yields. No additional additive is used in this reaction.

Nickel-catalyzed carboxylation of aryl and heteroaryl fluorosulfates using carbon dioxide

The development of efficient and practical methods to construct carboxylic acids using CO2 as a C1 synthon is of great importance. Nickel-catalyzed carboxylation of aryl fluorosulfates and heteroaryl fluorosulfates with CO2 is described, affording arene carboxylic acids with good to excellent yields under mild conditions. In addition, a one-pot phenol fluorosulfation/carboxylation is developed.

SO2F2-Mediated One-Pot Synthesis of Aryl Carboxylic Acids and Esters from Phenols through a Pd-Catalyzed Insertion of Carbon Monoxide

A one-pot Pd-catalyzed carbonylation of phenols into their corresponding aryl carboxylic acids and esters through the insertion of carbon monoxide has been developed. This procedure offers a direct synthesis of aryl carboxylic acids and esters from inexpensive and abundant starting materials (phenols, SO2F2 and CO) under mild conditions. This method tolerates a broad range of functional groups and is also applicable for the modification of complicated natural products.