36758-77-7 Usage
General Description
3-(Dimethylamino)-2-(4-methoxyphenyl)acrylonitrile is a chemical compound that belongs to the acrylonitrile class of chemicals. It is composed of a dimethylamino group, a 4-methoxyphenyl group, and an acrylonitrile moiety. 3-(DIMETHYLAMINO)-2-(4-METHOXYPHENYL)ACRYLONITRILE is used in organic synthesis as a key building block for the production of various pharmaceuticals, agrochemicals, and materials. It is also known for its fluorescent properties, making it valuable in the field of fluorescence spectroscopy and imaging. Additionally, it has potential application in the field of photodynamic therapy, a treatment that uses light-sensitive drugs to kill cancer cells. However, it is important to handle and use this compound with caution, as it may pose risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 36758-77-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,7,5 and 8 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 36758-77:
(7*3)+(6*6)+(5*7)+(4*5)+(3*8)+(2*7)+(1*7)=157
157 % 10 = 7
So 36758-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O/c1-14(2)9-11(8-13)10-4-6-12(15-3)7-5-10/h4-7,9H,1-3H3/b11-9-
36758-77-7Relevant articles and documents
Application of vinylogous carbamates and vinylogous aminonitriles to the regiospecific synthesis of uniquely functionalized pyrroles and quinolones
Gupton, John T.,Crawford, Evan,Mahoney, Matt,Clark, Evan,Curry, Will,Lane, Annie,Shimozono, Alex,Moore-Stoll, Veronica,Elofson, Kristen,Juekun, Wen,Newton, Micah,Yeudall, Scott,Jaekle, Elizabeth,Kanters, Rene,Sikorski, James A.
, p. 7408 - 7420 (2018/11/23)
Pyrroles and quinolones represent core structures, which are routinely found in both natural and synthetic bioactive substances. Consequently, the development of efficient and regiospecific methods for the preparation of such heterocycles with unique functionality is of some importance. We describe herein the regiospecific synthesis of 1,2,3,4-tetrasubstituted pyrroles containing polar substituents and such products are prepared from vinylogous carbamates and vinylogous aminonitriles. We also describe the regiospecific synthesis of 3-aryl containing 1,3,6-trisubstituted quinolones from vinylogous carbamates. The use of an amine exchange reaction to prepare precursors for the pyrrole and quinolone forming cyclizations represents a key factor in the strategy.
