3705-21-3 Usage
General Description
5-Hydroxyindole-3-carboxylic acid is an organic compound that is a derivative of the alkaloid indole. This chemical substance is predominantly involved in tryptophan metabolism in the human body. It is classified as a secondary metabolite, a molecule that is not directly involved in the normal growth, development, or reproduction of an organism. Recent studies have indicated that it may play a role in various biological functions and potentially in the mechanism of certain diseases. 5-HYDROXYINDOLE-3-CARBOXYLIC ACID is also broadly used in research fields to understand biological processes better. Its composition features a five-membered indole ring and a carboxylic acid group, contributing to its chemical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 3705-21-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,0 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3705-21:
(6*3)+(5*7)+(4*0)+(3*5)+(2*2)+(1*1)=73
73 % 10 = 3
So 3705-21-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO3/c11-5-1-2-8-6(3-5)7(4-10-8)9(12)13/h1-4,10-11H,(H,12,13)
3705-21-3Relevant articles and documents
Biocatalytic Cross-Coupling of Aryl Halides with a Genetically Engineered Photosensitizer Artificial Dehalogenase
Fu, Yu,Huang, Jian,Wu, Yuzhou,Liu, Xiaohong,Zhong, Fangrui,Wang, Jiangyun
supporting information, p. 617 - 622 (2021/02/03)
Devising artificial photoenzymes for abiological bond-forming reactions is of high synthetic value but also a tremendous challenge. Disclosed herein is the first photobiocatalytic cross-coupling of aryl halides enabled by a designer artificial dehalogenase, which features a genetically encoded benzophenone chromophore and site-specifically modified synthetic NiII(bpy) cofactor with tunable proximity to streamline the dual catalysis. Transient absorption studies suggest the likelihood of energy transfer activation in the elementary organometallic event. This design strategy is viable to significantly expand the catalytic repertoire of artificial photoenzymes for useful organic transformations.
