3705-50-8

Basic information

• Product Name: 2-amino-N,N-dimethyl-3-phenylpropanamide
• Synonyms: 2-amino-N,N-dimethyl-3-phenylpropanamide
• CAS NO: 3705-50-8
• Molecular Formula: C₁₁H₁₆N₂O
• Molecular Weight: 192.26
• Mol File: 3705-50-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-N,N-dimethyl-3-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-N,N-dimethyl-3-phenylpropanamide(3705-50-8)
• EPA Substance Registry System: 2-amino-N,N-dimethyl-3-phenylpropanamide(3705-50-8)

Safety Data

• Hazardous Substances Data: 3705-50-8(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 583-47-1 4-benzyl-oxazolidine-2,5-dione 
• 2578-86-1 DL-N-(carbobenzoxy)phenylalanine p-nitrophenyl ester 
• 150-30-1 Phenylalanine 
• 75768-06-8 DL-N-carbobenzoxyphenylalanine dimethylamide 

Downstream Products

• 29802-24-2 2-amino-1,1-N-dimethylamino-3-phenylpropane 
• 583-52-8 potassium oxalate 
• 582-25-2 Potassium benzoate 
• 124-40-3 dimethyl amine 
• 1000072-68-3 (2S)-N,N-dimethyl-3-phenyl-2-((3-phenylaziridin-2-yl)methylamino)propanamide 
• 29618-22-2 N-Benzyl-N-methyl-DL-phenylalanin-dimethylamid 
• 29618-21-1 N-Methyl-DL-phenylalanin-dimethylamid 
• 29618-51-7 N¹,N¹,N²-Trimethyl-3-phenyl-propane-1,2-diamine 
• 29674-13-3 N-Benzyl-DL-phenylalanin-dimethylamid 
• 91904-44-8 N,N-Dimethyl-DL-phenylalanin-dimethylamid 

Relevant articles and documents

Enantioselection in peptide bond formation

Selectivity in abiotic condensations of amino acids remains controversial and stereochemically little explored. We find that competitive activated couplings of N-acyl derivatives of glycine, alanine, valine, proline and phenylalanine with binary, ternary and quaternary mixtures of amides and esters of the same group of amino acids show little selectivity among the reactants, except with respect to configuration, where a consistent and significant preference for heterochiral outcomes, mostly >80%, is observed. One possible explanation of this selectivity predicts a predisposition to homochiral coupling under conditions that would require the two carboxyl functions to be co-facial in the activated complex.