37074-40-1

Basic information

• Product Name: 4'-Bromo-3'-methylacetophenone
• Synonyms: Ethanone, 1-(4-broMo-3-Methylphenyl)-;NSC 405623;3-Methyl-4-bromoacetophenone
• CAS NO: 37074-40-1
• Molecular Formula: C₉H₉BrO
• Molecular Weight: 213.07
• Product Categories: Aromatic Acetophenones & Derivatives (substituted)
• Mol File: 37074-40-1.mol
• Article Data: 11

Chemical Properties

• Melting Point: 31-32 °C
• Boiling Point: 284°C at 760 mmHg
• Flash Point: 88.8°C
• Appearance: /
• Density: 1.388g/cm³
• Vapor Pressure: 0.00307mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4'-Bromo-3'-methylacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Bromo-3'-methylacetophenone(37074-40-1)
• EPA Substance Registry System: 4'-Bromo-3'-methylacetophenone(37074-40-1)

Safety Data

• Hazardous Substances Data: 37074-40-1(Hazardous Substances Data)

Usage

General Description

4'-Bromo-3'-methylacetophenone is a chemical compound with the formula C10H11BrO. It is a derivative of acetophenone, which is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. The presence of a bromine atom and a methyl group on the phenyl ring makes 4'-bromo-3'-methylacetophenone a versatile building block in organic synthesis. It has been used in the preparation of heterocyclic compounds, as well as in the development of new materials and pharmaceuticals. The compound is also known for its use as a flavor and fragrance ingredient in the food and cosmetic industries. 4'-Bromo-3'-methylacetophenone has potential applications in the fields of medicinal chemistry, agrochemicals, and material science due to its diverse reactivity and structural characteristics.

InChI:InChI=1/C9H9BrO/c1-6-5-8(7(2)11)3-4-9(6)10/h3-5H,1-2H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 41963-20-6 4-bromo-3-methylbenzonirtile 
• 95-46-5 2-methylphenyl bromide 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 95-53-4 o-toluidine 
• 40664-73-1 4'-acetylamino-3'-methyl-acetophenone 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 75-16-1 methylmagnesium bromide 
• 170230-01-0 4-bromo-N-methoxy-3,N-dimethylbenzamide 
• 51930-77-9 1-(4-bromo-3-methylphenyl)ethan-1-ol 
• 78775-11-8 3-methyl-4-bromobenzaldehyde 
• 917-54-4 methyllithium 
• 7697-28-1 4-bromo-3-methylbenzoic acid 

Downstream Products

• 6939-93-1 4-bromo-isophthalic acid 
• 7697-28-1 4-bromo-3-methylbenzoic acid 
• 51930-77-9 1-(4-bromo-3-methylphenyl)ethan-1-ol 
• 792917-14-7 (4-bromo-3-methyl-phenyl)-acetic acid amide 
• 90841-15-9 1-bromo-4-isopropenyl-2-methyl-benzene 
• 90560-90-0 4-ethyl-1-bromo-2-methyl-benzene 
• 90560-53-5 1-bromo-2-methyl-4-vinyl-benzene 
• 92243-75-9 1-bromo-4-isopropyl-2-methyl-benzene 
• 91967-87-2 2-Methyl-4-aethyl-phenaethylalkohol 
• 91345-54-9 1-<2-Brommethyl>-2-methyl-4-aethyl-benzol 
• 92904-02-4 2-Methyl-4-isopropyl-phenethylalkohol 
• 92848-97-0 1-(2-Brom-ethyl)-2-methyl-4-isopropyl-benzol 
• 99249-77-1 1-(2-Methyl-4-ethyl-phenethyl)-2,6-dimethyl-cyclohexanol 
• 94760-70-0 1-(2-Methyl-4-isopropyl-phenethyl)-2,6-dimethyl-cyclohexanol 

Relevant articles and documents

Preparation method of velpatasvir intermediate

The invention provides a preparation method of a velpatasvir intermediate. According to the preparation method, ortho-toluidine is taken as an initial raw material, amino acetylation protection, Friedel-Crafts acylation, deamination protection, diazotization, and bromination are adopted so as to obtain 3-bromomethyl-4-bromoacetophenone; and alkylation with 7-hydroxy-1-tetralone, intramolecular coupling, and bromination are adopted so as to obtain 9-bromo-3-(2-bromoacetyl)-10, 11-dihydro-5H-benzo[d]naphtho[2,3-b]pyran-8(9H)-one. The yield and the purity of the velpatasvir intermediate preparedvia the preparation method are high, cost is low, and large size production is convenient to realize.

ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

A compound of formula (I): wherein the substituents are as defined in the description. Medicinal products containing the same which are useful in treating or preventing pathologies which are the result of activation of the RhoA/ROCK pathway and phosphorylation of the myosin light chain.

Modulators of methyl modifying enzymes, compositions and uses thereof

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.