37138-82-2 Usage
General Description
2,4-Dichloro-6-nitroanisole is a chemical compound with the molecular formula C7H6Cl2NO3. It is a nitrophenyl ether, with chlorine atoms attached to the second and fourth carbon atoms, and a nitro group attached to the sixth carbon atom. 2,4-DICHLORO-6-NITROANISOLE is mainly used in the synthesis of pharmaceuticals and as an intermediate in the production of agrochemicals. It is a yellow crystalline solid with a melting point of 55-57°C and is insoluble in water but soluble in organic solvents. 2,4-Dichloro-6-nitroanisole is also a potential mutagen and should be handled with care.
Check Digit Verification of cas no
The CAS Registry Mumber 37138-82-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,1,3 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 37138-82:
(7*3)+(6*7)+(5*1)+(4*3)+(3*8)+(2*8)+(1*2)=122
122 % 10 = 2
So 37138-82-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5Cl2NO3/c1-13-7-5(9)2-4(8)3-6(7)10(11)12/h2-3H,1H3
37138-82-2Relevant articles and documents
Relative reactivity of methyl iodide to ethyl iodide in nucleophilic substitution reactions in acetonitrile and partial desolvation accompanying activation
Kondo, Yasuhiko,Urade, Miyuki,Yamanishi, Yukari,Chen, Xinyu
, p. 1449 - 1454 (2007/10/03)
Through the examination of empirical correlations involving activation parameters for nucleophilic substitution of methyl iodide and of ethyl iodide, nucleophiles have been classified into three series: (1) nucleophiles with two equivalent reaction sites, (2) nucleophiles with a chlorine atom in the para-position, and (3) nucleophiles with a single reaction site. Three types of partial desolvation processes accompanying activation have been deduced on the basis of these classifications. A major factor determining the relative reactivity of methyl iodide to ethyl iodide in the substitution reaction of an anionic nucleophile having a single reaction site in acetonitrile (kMeI/kEtI) is suggested to be partial desolvation around the nucleophilic center on going from reactant to transition-state.
