3715-90-0

Basic information

• Product Name: tramazoline hydrochloride
• Synonyms: tramazoline hydrochloride;TramazolinHCl;Tramazolinhydrochlorid;C12780;2-[(5,6,7,8-Tetrahydronaphthalene-1-yl)amino]-2-imidazoline·hydrochloride;Towk
• CAS NO: 3715-90-0
• Molecular Formula: C13H17N3.ClH
• Molecular Weight: 251.759
• EINECS: 223-064-3
• Mol File: 3715-90-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 172-174°
• Boiling Point: 353°C at 760 mmHg
• Flash Point: 167.3°C
• Appearance: /
• Vapor Pressure: 3.7E-05mmHg at 25°C
• Solubility: Soluble in water and in ethanol (96 per cent).
• CAS DataBase Reference: tramazoline hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: tramazoline hydrochloride(3715-90-0)
• EPA Substance Registry System: tramazoline hydrochloride(3715-90-0)

Safety Data

• Hazardous Substances Data: 3715-90-0(Hazardous Substances Data)

Usage

Description

Tramazoline hydrochloride, also known as Tramazoline, is a white or almost white crystalline powder. It is an active pharmaceutical ingredient with various applications in the medical field. As an imidazoline derivative, it has a range of pharmacological properties that make it a versatile compound for different uses.

Uses

Used in Ophthalmology:
Tramazoline hydrochloride is used as a vasoconstrictor in ophthalmology for reducing redness and eye irritation. Its vasoconstrictive properties help to alleviate the symptoms of eye conditions by narrowing the blood vessels in the eye, thus reducing redness and inflammation.
Used in Nasal Sprays:
In the pharmaceutical industry, tramazoline hydrochloride is used as a decongestant in nasal sprays for the temporary relief of nasal congestion. Its decongestant action helps to relieve the symptoms of nasal congestion by constricting the blood vessels in the nasal passages, providing a temporary sense of relief.
Used in Local Anesthetics:
Tramazoline hydrochloride is also used as a component in local anesthetic formulations. Its anesthetic properties help to numb the area of application, providing pain relief and reducing discomfort during medical procedures.
Used in Antimicrobial Applications:
In the field of antimicrobial agents, tramazoline hydrochloride is used for its antimicrobial properties. It can be effective against certain bacteria and fungi, making it a useful compound in the development of antimicrobial products.
Used in Veterinary Medicine:
In veterinary medicine, tramazoline hydrochloride is used as a vasoconstrictor and decongestant in animals, similar to its applications in human medicine. It helps to alleviate symptoms of nasal congestion and eye irritation in pets, providing relief and comfort.

InChI:InChI=1/C13H17N3.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)16-13-14-8-9-15-13;/h3,5,7H,1-2,4,6,8-9H2,(H2,14,15,16);1H