372199-89-8

Basic information

• Product Name: N-(cyclohexyl(tosyl)methyl)benzamide
• Synonyms: N-(cyclohexyl(tosyl)methyl)benzamide
• CAS NO: 372199-89-8
• Molecular Weight: 371.5
• Mol File: 372199-89-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(cyclohexyl(tosyl)methyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(cyclohexyl(tosyl)methyl)benzamide(372199-89-8)
• EPA Substance Registry System: N-(cyclohexyl(tosyl)methyl)benzamide(372199-89-8)

Safety Data

• Hazardous Substances Data: 372199-89-8(Hazardous Substances Data)

Upstream product

• 55-21-0 benzamide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 2043-61-0 cyclohexanecarbaldehyde 
• 536-57-2 p-toluene sulfinic acid 

Relevant articles and documents

Enantioselective Synthesis of α-Amidoboronates Catalyzed by Planar-Chiral NHC-Cu(I) Complexes

The first highly selective catalytic hydroboration of alkyl-substituted aldimines to provide medicinally relevant α-amidoboronates is disclosed. The Cu(I)-catalyzed borylation proceeds with excellent facial selectivity when a set of planar-chiral N-heterocyclic carbenes (NHCs) were employed as ligands. Density functional theory computations suggest that interactions between BPin and the planar-chiral catalyst are responsible for the observed stereoselectivity. Important pharmacophores, such as the boronate analogue of isoleucine, can be prepared using a chromatography-free protocol starting from commercially available reagents. The application of these NHC ligands in these Cu(I)-catalyzed processes offers a significant contribution to existing strategies for laboratory-scale preparation of enantioenriched α-amidoboronates.

Synthesis of α-amido ketones via organic catalysis: Thiazolium-catalyzed cross-coupling of aldehydes with acylimines [12]

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