374081-61-5

Basic information

• Product Name: 3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-bromo-3H-imidazole-4-carbonitrile
• Synonyms: 3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-bromo-3H-imidazole-4-carbonitrile
• CAS NO: 374081-61-5
• Molecular Weight: 574.474
• Mol File: 374081-61-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-bromo-3H-imidazole-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-bromo-3H-imidazole-4-carbonitrile(374081-61-5)
• EPA Substance Registry System: 3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-bromo-3H-imidazole-4-carbonitrile(374081-61-5)

Safety Data

• Hazardous Substances Data: 374081-61-5(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 374081-60-4 3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-bromo-3H-imidazole-4-carbaldehyde oxime 
• 13035-61-5 1,2,3,5-tetraacetylribose 
• 374081-58-0 1-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-4,5-dibromo-1H-imidazole 
• 374081-59-1 3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-bromo-3H-imidazole-4-carbaldehyde 
• 437614-21-6 4,5-dibromo-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole 
• 437614-22-7 4,5-dibromo-1-(β-D-ribofuranosyl)imidazole 

Downstream Products

• 374081-62-6 2-[1-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-cyano-1H-imidazol-4-ylsulfanyl]-acetamide 
• 374081-68-2 6-[3-((2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H-imidazol-4-yl]-pyrimidin-4-ylamine 
• 437614-55-6 2-amino-6-[3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H-imidazol-4-yl]-3H-pyrimidin-4-one 
• 374081-67-1 3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H-8-thia-1,3,4,6-tetraaza-cyclopenta[a]inden-7-ylamine 
• 374081-63-7 6-amino-1-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-1H-thieno[2,3-d]imidazole-5-carboxylic acid amide 
• 374081-66-0 3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-7-methylsulfanyl-3H-8-thia-1,3,4,6-tetraaza-cyclopenta[a]indene 
• 374081-69-3 5-amino-3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H,6H-8-thia-1,3,4,6-tetraaza-cyclopenta[a]inden-7-one 
• 437614-57-8 6-[3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H-imidazol-4-yl]-3H-pyrimidin-4-one 
• 374081-65-9 3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H,6H-8-thia-1,3,4,6-tetraaza-cyclopenta[a]indene-7-thione 
• 374081-64-8 3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H,6H-8-thia-1,3,4,6-tetraaza-cyclopenta[a]inden-7-one 
• 374081-64-8 3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H-8-thia-1,3,4,6-tetraaza-cyclopenta[a]inden-7-ol 
• 374081-65-9 3-(3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3H-8-thia-1,3,4,6-tetraaza-cyclopenta[a]indene-7-thiol 

Relevant articles and documents

"Fleximers". Design and synthesis of a new class of novel shape-modified nucleosides(1).

A new class of shape-modified nucleosides is introduced. These novel "fleximers" feature the purine ring systems of adenosine, inosine, and guanosine split into their individual imidazole and pyrimidine components (as in 1-3). This structural modification serves to introduce flexibility into the nucleoside while still retaining the elements essential for recognition. As a consequence, these novel fleximers should find use as bioprobes for investigating enzyme-coenzyme binding sites as well as nucleic acid and protein interactions. Their design and synthesis are described.