37458-57-4

Basic information

• Product Name: 2-(p-methoxyphenyl)pyrrolo[3,4-b]quinoxaline-1,3-dione
• Synonyms: 2-(p-methoxyphenyl)pyrrolo[3,4-b]quinoxaline-1,3-dione
• CAS NO: 37458-57-4
• Molecular Weight: 305.293
• Mol File: 37458-57-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(p-methoxyphenyl)pyrrolo[3,4-b]quinoxaline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(p-methoxyphenyl)pyrrolo[3,4-b]quinoxaline-1,3-dione(37458-57-4)
• EPA Substance Registry System: 2-(p-methoxyphenyl)pyrrolo[3,4-b]quinoxaline-1,3-dione(37458-57-4)

Safety Data

• Hazardous Substances Data: 37458-57-4(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 34379-53-8 2,3-dichloro-N-(4-methoxyphenyl)maleimide 
• 256945-43-4 3-chloro-1-(4-methoxy-phenyl)-4-phenylamino-pyrrole-2,5-dione 

Relevant articles and documents

Generality and scope of the synthesis of 2-arylpyrrolo[3,4-b] quinoxaline-1,3-diones from 2,3-dichloro-N-arylmaleimides. II

Nucleophilic substitution of 2,3-dichloro-N-arylmaleimides (1) and (2) with a series of arylamines gives 2-arylamino-3-chloro-N-arylmaleimides (3) and (4), respectively. When 4 is treated with sodium azide at room temperature, it cyclizes to the 2-(p-methoxyphenyl)pyrrolo[3,4-b]quinoxaline- 1,3-diones (5). Under the same conditions, the 2-(p-nitrophenyl) analogue (3) fails to cyclize. Ring closure is also subject to the steric and electronic effects of substituents in the nucleophile.