374633-27-9 Usage
General Description
4-Bromo-6-indolecarboxylic acid is a chemical compound with the molecular formula C9H6BrNO2. It is an organic compound belonging to the class of indole derivatives, and it contains a bromo substituent at position 4 and a carboxylic acid group at position 6 of the indole ring. 4-BROMO-6-INDOLECARBOXYLIC ACID is commonly used as a building block in the synthesis of various pharmaceuticals and bioactive molecules. It has also been studied for its potential anti-inflammatory and antitumor properties. Additionally, 4-bromo-6-indolecarboxylic acid has been used as a ligand in coordination chemistry and in the preparation of metal-based catalysts and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 374633-27-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,4,6,3 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 374633-27:
(8*3)+(7*7)+(6*4)+(5*6)+(4*3)+(3*3)+(2*2)+(1*7)=159
159 % 10 = 9
So 374633-27-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H6BrNO2/c10-7-3-5(9(12)13)4-8-6(7)1-2-11-8/h1-4,11H,(H,12,13)
374633-27-9Relevant articles and documents
ACYLHYDRAZONES AS KINASE MODULATORS
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Page/Page column 39, (2010/11/24)
Abstract The invention is directed to acylhydrazones compounds of Formula I: where R1, R2 and A are as defined herein, the use of such compounds as protein tyrosine kinase modulators, particularly inhibitors of c-Met, and the use of such compounds to reduce or inhibit kinase activity of c-Met in a cell or a subject, and modulate c-Met expression in a cell or subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to c-Met. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as cancers and other cell proliferative disorders.
