37589-80-3 Usage
Uses
GTP-γ-S has been used: in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα) to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants
General Description
Guanosine 5′-O-(3-thiotriphosphate), tetralithium salt (GTP-γ-S) is a non-hydrolysable analog of GTP. It is an inhibitor of phosphodiesterase in photoreceptors.
Biochem/physiol Actions
Guanosine 5′-O-(3-thiotriphosphate) (GTP-γ-S) activates guanine-nucleotide-binding proteins and is slowly hydrolyzed enzymatically. It inhibits guanosine triphosphatase (GTPases) more potently than guanosine triphosphate (GTP),
Check Digit Verification of cas no
The CAS Registry Mumber 37589-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,5,8 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 37589-80:
(7*3)+(6*7)+(5*5)+(4*8)+(3*9)+(2*8)+(1*0)=163
163 % 10 = 3
So 37589-80-3 is a valid CAS Registry Number.
