37593-05-8

Basic information

• Product Name: 4-N-NONYLACETOPHENONE
• Synonyms: P-NONYLACETOPHENONE;4'-N-NONYLACETOPHENONE;4-N-NONYLACETOPHENONE;1-(4-NONYLPHENYL)ETHAN-1-ONE
• CAS NO: 37593-05-8
• Molecular Formula: C₁₇H₂₆O
• Molecular Weight: 246.39
• Mol File: 37593-05-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 159 °C
• Flash Point: 159-161°C/2mm
• Appearance: /
• Density: 0.914 g/cm³
• Vapor Pressure: 2.95E-05mmHg at 25°C
• Refractive Index: 1.5050
• CAS DataBase Reference: 4-N-NONYLACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-NONYLACETOPHENONE(37593-05-8)
• EPA Substance Registry System: 4-N-NONYLACETOPHENONE(37593-05-8)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 37593-05-8(Hazardous Substances Data)

Usage

General Description

4-N-Nonylacetophenone is a chemical compound that belongs to the group of acetophenones, which are organic compounds with a characteristic ketone group. It is commonly used in the manufacturing of various products such as fragrances, flavors, and pharmaceuticals. This chemical is known for its sweet, floral and almond-like smell, making it a popular ingredient in the cosmetic and fragrance industry. In addition to its aromatic properties, 4-N-Nonylacetophenone also exhibits anti-microbial and anti-inflammatory properties, making it useful in the development of pharmaceutical products. However, it is important to handle this chemical with caution, as it may be irritating to the skin and eyes, and can cause respiratory issues if inhaled in large quantities.

InChI:InChI=1/C17H26O/c1-3-4-5-6-7-8-9-10-16-11-13-17(14-12-16)15(2)18/h11-14H,3-10H2,1-2H3

Upstream product

• 1081-77-2 n-nonylbenzene 
• 75-36-5 acetyl chloride 
• 4282-42-2 1-iodononane 
• 13329-40-3 4-Iodoacetophenone 
• 766-04-1 benzyllithium 
• 693-58-3 1-Bromononane 
• 108-86-1 bromobenzene 

Downstream Products

• 94775-84-5 3-(4-n-Nonylphenyl)-6-n-propylpyridazine 
• 94775-74-3 2-Hydroxy-1-(4-nonyl-phenyl)-heptane-1,4-dione 
• 94775-65-2 Potassium; 2-[1-hydroxy-2-(4-nonyl-phenyl)-2-oxo-ethyl]-3-oxo-hexanoate 
• 46843-32-7 p-nonylstyrene 
• 82760-75-6 2,4-dioxo-4-(4-nonylphenyl)-1-butanoic acid 
• 123501-86-0 1-ethynyl-4-nonylbenzene 
• 123501-85-9 1-(4-nonylphenyl)-1-chloroethene 
• 100-21-0 terephthalic acid 
• 64128-41-2 C₃₀H₄₃NO₃ 
• 93811-41-7 α-<4-Nonyl-phenyl>-aethylamin 
• 14333-91-6 p-n-Nonylphenylglyoxal 
• 82760-74-5 methyl 2,4-dioxo-4-(4-nonylphenyl)-1-butanoate 

Relevant articles and documents

Copper(II)-catalyzed preparation of alkylindium compounds and applications in cross-coupling reactions both in aqueous media

An efficient water-based method for the synthesis of alkylindium compound in the presence of a catalytic amount of cheap and readily available CuSO4·5H2O (10 mol%) was developed. The thus-generated alkylindium compounds effectively underwent palladium-catalyzed cross-coupling reactions with a myriad of aryl halides in aqueous media, leading to the cross-coupled products in modest to high yields. The mildness of the formed alkyl organometallics allowed the tolerance to various important functional groups incorporated in both substrates of alkyl iodides and aryl halides.

Preparation of Alkyl Indium Reagents by Iodine-Catalyzed Direct Indium Insertion and Their Applications in Cross-Coupling Reactions

An efficient method for the synthesis of alkyl indium reagent by means of an iodine-catalyzed direct indium insertion into alkyl iodide in THF is reported. The thus-generated alkyl indium reagents effectively underwent Pd-catalyzed cross-coupling reactions with various aryl halides, exhibiting good compatibility to a variety of sensitive functional groups. By replacing THF with DMA and using 0.75 equiv of iodine, less reactive alkyl bromide could be used as substrate for indium insertion with equal ease.

Application of novel coupling reaction to preparing carbon-carbon bond structured compounds

The invention relates to application of a novel coupling reaction to preparing carbon-carbon bond structured compounds and mainly provides a reaction between alkyl indium compounds and halides. The reaction between the alkyl indium compounds and the halides can produce corresponding carbon-carbon structured products. The novel coupling reaction is high in process yield, broad in functional group tolerance and good in compatibility.