37597-30-1Relevant articles and documents
The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites
Hsu, Hao-Chi,Tong, Simon,Zhou, Yuchen,Elmes, Matthew W.,Yan, Su,Kaczocha, Martin,Deutsch, Dale G.,Rizzo, Robert C.,Ojima, Iwao,Li, Huilin
, p. 3454 - 3462 (2017)
Human FABP5 and FABP7 are intracellular endocannabinoid transporters. SBFI-26 is an α-truxillic acid 1-naphthyl monoester that competitively inhibits the activities of FABP5 and FABP7 and produces antinociceptive and anti-inflammatory effects in mice. The
SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins
Yan, Su,Elmes, Matthew W.,Tong, Simon,Hu, Kongzhen,Awwa, Monaf,Teng, Gary Y.H.,Jing, Yunrong,Freitag, Matthew,Gan, Qianwen,Clement, Timothy,Wei, Longfei,Sweeney, Joseph M.,Joseph, Olivia M.,Che, Joyce,Carbonetti, Gregory S.,Wang, Liqun,Bogdan, Diane M.,Falcone, Jerome,Smietalo, Norbert,Zhou, Yuchen,Ralph, Brian,Hsu, Hao-Chi,Li, Huilin,Rizzo, Robert C.,Deutsch, Dale G.,Kaczocha, Martin,Ojima, Iwao
, p. 233 - 252 (2018/05/28)
Fatty acid binding proteins (FABPs) serve as critical modulators of endocannabinoid signaling by facilitating the intracellular transport of anandamide and whose inhibition potentiates anandamide signaling. Our previous work has identified a novel small-m
Unambiguous Proof of Nitrile Formation from Pyrazine Skeleton through Photo-Oxidative Degradation. Isolation and Structural Determination of Photodegraded Product of Amorphous Poly(2,5-distyrylpyrazine)
Hashimoto, Yukihiko,Adegawa, Yutaka,Hasegawa, Masaki,Onodera, Kazuyuki,Sakuragi, Hirochika,Tokumaru, Katsumi
, p. 1043 - 1045 (2007/10/02)
In the presence of oxygen, amorphous poly(2,5-distyrylpyrazine) film was readily photodegraded, accompanied by cleavage of the pyrazine rings in the main chain.From the photodegraded film, t-2,c-4-diphenylcyclobutane-r-1,t-3-dicarbonitrile was isolated in
