37614-58-7

Basic information

• Product Name: 3-(4-BROMO-PHENYL)-PROP-2-YN-1-OL
• Synonyms: 3-(4-BROMO-PHENYL)-PROP-2-YN-1-OL;AKOS PRN-0011;3-(4-BroMophenyl)-2-propyn-1-ol
• CAS NO: 37614-58-7
• Molecular Formula: C₉H₇BrO
• Molecular Weight: 211.06
• Mol File: 37614-58-7.mol
• Article Data: 51

Chemical Properties

• Boiling Point: 304.2 °C at 760 mmHg
• Flash Point: 137.8 °C
• Appearance: /
• Density: 1.58 g/cm³
• CAS DataBase Reference: 3-(4-BROMO-PHENYL)-PROP-2-YN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-BROMO-PHENYL)-PROP-2-YN-1-OL(37614-58-7)
• EPA Substance Registry System: 3-(4-BROMO-PHENYL)-PROP-2-YN-1-OL(37614-58-7)

Safety Data

• Hazardous Substances Data: 37614-58-7(Hazardous Substances Data)

Usage

General Description

3-(4-Bromo-phenyl)-prop-2-yn-1-ol is a chemical compound with the molecular formula C9H7BrO. It is a derivative of propargyl alcohol that contains a bromine atom and a phenyl group. 3-(4-BROMO-PHENYL)-PROP-2-YN-1-OL is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various molecules. It is also known for its potential biological activities and has been studied for its antibacterial, antifungal, and anticancer properties. 3-(4-Bromo-phenyl)-prop-2-yn-1-ol is a versatile compound with diverse applications in the field of chemistry and biomedicine.

Upstream product

• 589-87-7 1,4-bromoiodobenzene 
• 107-19-7 propargyl alcohol 
• 50-00-0 formaldehyd 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 106-37-6 1.4-dibromobenzene 
• 7681-65-4 copper(I) iodide 
• 136350-66-8 1-bromo-4-(2,2-dibromovinyl)benzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 16116-78-2 (4-bromophenyl)(trimethylsilyl)acetylene 
• 19070-80-5 n-<(trimethylsiloxy)methyl>phthalimide 
• 1000999-91-6 2-((3-(4-bromophenyl)prop-2-yn-1-yl)oxy)tetrahydro-2H-pyran 
• 33458-10-5 1-bromo-4-(1,2-dibromoethyl)benzene 
• 2039-82-9 1-bromo-4-ethenyl-benzene 

Downstream Products

• 76457-91-5 3-(4-bromophenyl)prop-2-ynal 
• 278168-74-4 1-bromo-4-(3-phenylprop-1-yn-1-yl)benzene 
• 60214-07-5 5-(4-bromophenyl)penta-2,4-diyn-1-ol 
• 60214-13-3 1-bromo-4-(1,3-butadiyn-1-yl)benzene 
• 116632-39-4 2-methyl-4-bromoiodobenzene 
• 699119-05-6 1-bromo-4-iodo-2,5-dimethylbenzene 
• 1122474-50-3 (S)-5-(4-bromobenzyl)-3-isopropyl-4-tosyl-3,4-dihydro-2H-1,4-oxazine 
• 452296-51-4 (Z)-3-(4-bromophenyl)-3-iodoprop-2-en-1-ol 
• 1343516-32-4 3-(3-(4-bromophenyl)-1-methoxyprop-2-ynyl)-3-methylpentane-2,4-dione 
• 1343516-46-0 (E)-1,5-bis(4-bromophenyl)-2-(methoxymethyl)pent-2-en-4-yn-1-one 
• 869209-24-5 (Z)-[4-[3-(4-bromophenyl)-5-phenylpent-2-en-4-ynyloxy]-2-methylphenoxy]acetic acid methyl ester 

Relevant articles and documents

Organocatalytic Regio- and Enantioselective N-Alkylation of Isoxazol-5-ones

A chiral phosphoric acid catalyzed regio- and enantioselective reaction between 1-acylamino-3-arylprop-2-yn-1-ols and isoxazol-5-ones has been developed for the first time. With the established protocol, N-alkylation of isoxazol-5-ones was achieved, affording enantioenriched N,N-acetals in 74–99 % yield with 72–88 % ee.

Bi(OTf)3-catalyed One-pot Synthesis of α-Halo-β-amino Ketones and Acyl Aziridines from 3-Aryl Propargyl Alcohols

A Bi(OTf)3-catalyed reaction of 3-aryl propargyl alcohols with sulfonamide and halogen source was firstly investigated, which provided a facile route for the synthesis of a large variety of α-halo-β-amino ketones. The key intermediates, β-amino

When Gold Meets Perfumes: Synthesis of Olfactive Compounds via Gold-Catalyzed Cycloisomerization Reactions

An efficient, and mild synthetic route for the preparation of functionalized volatile oxa-bicyclo[4.1.0]-hept-4-ene (29 compounds, 44-98% isolated yields) has been developed relying on the association of IPrAuCl with NaBArF. The remarkable selectivity was demonstrated on a 1 g and 25 g scale with low catalyst loadings. The synthetic utility of these low-molecular-weight enols was further demonstrated by the derivatization of some adducts and by the unprecedented olfactory evaluation of all bicyclic derivatives.