376584-62-2

Basic information

• Product Name: 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLIN-1-ONE
• Synonyms: 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLIN-1-ONE;1-Isoindolinone-5-boronic acid pinacol ester;5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-2,3-dihydroisoindol-1-one;1H-Isoindol-1-one, 2,3-dihydro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-isoindol-1-one;1-Oxoisoindoline-5-boronic acid, pinacol ester;5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one, 2,3-Dihydro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-isoindol-1-one;2,3-Dihydro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-isoindol-1-one
• CAS NO: 376584-62-2
• Molecular Formula: C₁₄H₁₈BNO₃
• Molecular Weight: 259.12
• Product Categories: Organic boronic acid
• Mol File: 376584-62-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 476.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.16±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.95±0.20(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLIN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLIN-1-ONE(376584-62-2)
• EPA Substance Registry System: 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLIN-1-ONE(376584-62-2)

Safety Data

• Hazardous Substances Data: 376584-62-2(Hazardous Substances Data)

Usage

Description

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one is a synthetic compound that possesses a unique chemical structure featuring a dioxaborolan-2-yl group and an isoindolin-1-one moiety. 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLIN-1-ONE is known for its potential applications in various fields due to its versatile chemical properties.

Uses

Used in Pharmaceutical Industry:
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one is used as an intermediate in the synthesis of pharmaceutical compounds for its ability to facilitate the formation of complex molecular structures. Its unique chemical properties make it a valuable building block in the development of new drugs.
Used in Chemical Research:
In the field of chemical research, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one serves as a key compound for studying the reactivity and properties of dioxaborolan-2-yl and isoindolin-1-one groups. This helps researchers to better understand the underlying mechanisms of various chemical reactions and develop new synthetic methodologies.
Used in Material Science:
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one is utilized in material science as a component in the development of novel materials with specific properties. Its incorporation into polymers or other materials can lead to the creation of materials with enhanced characteristics, such as improved stability, reactivity, or selectivity.
Used in Catalyst Design:
As a synthetic compound, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one is also used in the design of catalysts for various chemical reactions. Its unique structure can be employed to create catalysts with high selectivity and activity, which can be applied in a wide range of industrial processes.
Overall, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one is a versatile synthetic compound with a broad range of applications across different industries, including pharmaceuticals, chemical research, material science, and catalyst design. Its unique chemical properties make it a valuable asset in the development of new technologies and products.

Upstream product

• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 

Downstream Products

• 1345879-86-8 4-[3-difluoromethoxy-2-methoxy-6-(1oxo-2,3-dihydro-1H-isoindol-5-yl)phenoxymethyl]benzenamide 
• 1345879-71-1 5-(4-(difluoromethoxy)-2-ethoxy-3-methoxyphenyl)isoindolin-1-one 
• 1345879-75-5 5-(4-(difluoromethoxy)-3-methoxy-2-(3-hydroxy-2,2-dimethylpropoxy)phenyl)-2,3-dihydroisoindol-1-one 
• 1345879-76-6 5-(4-(difluoromethoxy)-3-methoxy-2-(3-methyloxetan-3-ylmethoxy)phenyl)-2,3-dihydroisoindol-1-one 
• 1345879-77-7 5-(4-(difluoromethoxy)-2-(3-hydroxymethyloxetan-3-ylmethoxy)-3-methoxyphenyl)-2,3-dihydroisoindol-1-one 
• 1345879-79-9 5-(4-difluoromethoxy-3-methoxy-2-(3-methoxymethyloxetan-3-ylmethoxy)phenyl)-2,3-dihydroisoindol-1-one 
• 1345879-81-3 4-[3-difluoromethoxy-2-methoxy-6-(1oxo-2,3-dihydro-1H-isoindol-5-yl)phenoxymethyl]benzenesulfonamide 
• 1345879-83-5 5-[4-difluoromethoxy-2-(4-methanesulfonylbenzyloxy)-3-methoxyphenyl]-2,3-dihydroisoindol-1-one 
• 1345879-88-0 2-[3-difluoromethoxy-2-methoxy-6-(1oxo-2,3-dihydro-1H-isoindol-5-yl)phenoxy]-N-propylacetamide 
• 1613639-03-4 2-[5-(1-oxo-2,3-dihydro-1H-isoindol-5-yl)pyridin-3-ylamino]-2-phenylacetamide 
• 1313397-54-4 5-(3-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)phenyl)isoindolin-1-one 
• 1313398-41-2 3-(1-oxoisoindolin-5-yl)benzaldehyde 
• 1313397-53-3 5-(4-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)phenyl)isoindolin-1-one 
• 1313398-37-6 4-(1-oxoisoindolin-5-yl)benzaldehyde 

Relevant articles and documents

BIARYL PHOSPHODIESTERASE 1NHIBITORS

Novel biaryl compounds with phosphodiesterase inhibitory activity of the general formula (I), wherein R1, R2, R3, X, Y, Z1, Z2, Z3, and Z4 have the meanings defined herein, as well as their use as therapeutic agents in the treatment of inflammatory diseases and conditions