37686-85-4

Basic information

• Product Name: S-(-)-TERGURIDE MALEATE SALT
• Synonyms: n,n-diethyl-n’-((8-alpha)-6-methylergolin-8-yl)urea(z)-2-butenedioate;terguridehydrogenmaleate;trans-9,10-dihydrolisuridehydrogenmaleate;vufb6638;S-(-)-TERGURIDE MALEATE SALT;N,N-diethyl-N'-[(8alpha)-6-methylergolin-8-yl]uronium hydrogen maleate (1:1);Terguride acid maleate;S(-)-N,N-Diethyl-Nμ-[(8a)-6-methylergolin-8-yl]urea
• CAS NO: 37686-85-4
• Molecular Formula: C24H32N4O5
• Molecular Weight: 456.53
• EINECS: 253-625-8
• Mol File: 37686-85-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 190-191°
• Boiling Point: 766.9°C at 760 mmHg
• Flash Point: 417.6°C
• Appearance: /
• Vapor Pressure: 9.83E-25mmHg at 25°C
• CAS DataBase Reference: S-(-)-TERGURIDE MALEATE SALT(CAS DataBase Reference)
• NIST Chemistry Reference: S-(-)-TERGURIDE MALEATE SALT(37686-85-4)
• EPA Substance Registry System: S-(-)-TERGURIDE MALEATE SALT(37686-85-4)

Safety Data

• Hazard Codes: Xn
• Statements: 62
• Safety Statements: 53-36/37/39-45
• RTECS: YS9379000
• Hazardous Substances Data: 37686-85-4(Hazardous Substances Data)

Usage

General Description

S-(-)-Terguride Maleate Salt is a chemical compound formulated as a salt form of the Terguride drug. Terguride, also known as trans-dihydrolisuride, is a serotonin receptor antagonist typically used for Parkinson's disease and hyperprolactinemia. The drug inhibits the secretion of prolactin and exhibits strong antagonistic effects on serotonin (5-HT) receptors, primarily in 5-HT2A and 5-HT2C receptors. As the S-(-)-isomer of Terguride, this salt compound is believed to possess a higher level of biological activity. This chemical compound is strictly used for laboratory research purposes.

InChI:InChI=1/C20H28N4O.C4H4O4/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14;5-3(6)1-2-4(7)8/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,16+,18+;/m0./s1