377-38-8Relevant articles and documents
HIGHLY FLUORINATED HETEROCYCLES. PART XVI. POLYFLUORINATED DERIVATIVES OF 1-METHYLPYRROLIDINE, 1-METHYLPYRROL-3-INE AND 1-METHYLPYRROLE
Coe, Paul L.,Holton, Andrew G.,Sleigh, John H.,Smith, Peter,Tatlow, John Colin
, p. 287 - 298 (1983)
Fluorination of 1-methylpyrrole with cobalt(III) fluoride gave six major products, 1-fluoromethyl- and 1-difluoromethyl- -octa-,-3H-hepta-, and -3H,4H-hexa-fluoropyrrolidine.Similar fluorination of 1-methyl-pyrrolidine gave better total recoveries of the same six products, together with 1-trifluoromethyloctafluoropyrrolidine, and 1-fluoromethyl- and 1-difluoromethyl- -2H-heptafluoropyrrolidine. 1-Fluoromethyl- and 1-difluoromethyl- -3H-heptafluoropyrrolidine each gave the corresponding polyfluoropyrrol-3-ine on dehydrofluorination with potassium hydroxide, but the 1-difluoromethyl-2H-heptafluoride could not be dehydrofluorinated. 1-Methyl- and 1-fluoromethyl- -3H,4H-hexafluoropyrrolidine similarly gave the corresponding 3H-3-ine, but no pyrrole.Reaction of 1-methyl-3H,4H-hexafluoropyrrolidine with 'old' aluminium chloride gave a little 1-methyl-2,5-dichlorodifluoropyrrole, the only fluoropyrrole we have obtained so far.Freshly sublimed AlCl3 afforded 1-methyltetrachloropyrrole (obtained also from 1-methylpyrrole and sulphuryl chloride) : fluorination of this with KCo(III)F4 gave 1-methyl- and 1-fluoromethyl- -3,4-dichloro-tetrafluoropyrrol-3-ine.
Preparation method of fluorine-containing dicarboxylic acid
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Paragraph 0045-0047, (2020/07/12)
The invention discloses a preparation method of fluorine-containing dicarboxylic acid, which comprises: by using fluorine-containing cycloolefin as a raw material, performing oxidation with an oxidantunder the actions of a solvent and a catalyst to generate the corresponding fluorine-containing dicarboxylic acid. According to the method, a mixed solvent composed of the organic solvent and water is used as a solvent system of an oxidation reaction, the fluorine-containing cycloolefin is oxidized into corresponding fluorine-containing dicarboxylic acid by using the oxidant under the action of the catalyst, and the method has the characteristics of simple operation, stable process, safety, short reaction time, high yield and high product quality, and is suitable for large-scale production.
Preparation method of fluorine-containing carboxylic acid
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Paragraph 0033; 0035-0036, (2020/07/12)
The invention discloses a preparation method of fluorine-containing carboxylic acid. The method comprises the following steps: reacting fluorine-containing carboxylate used as a raw material with an acylating chlorination reagent to obtain a corresponding mixture of fluorine-containing acyl chloride and fluorine-containing anhydride, and hydrolyzing and drying the mixture of fluorine-containing acyl chloride and fluorine-containing anhydride to obtain high-purity fluorine-containing carboxylic acid. The method provided by the invention is suitable for post-treatment of fluorine-containing carboxylic acid prepared by a fluorine-containing olefin (monoolefine, diene, cycloolefin and the like) oxidation method, replaces the traditional strong acid acidification and ether continuous extractionprocess, and is simpler, more convenient and more applicable; and the method can also be used for recovering and purifying a fluorine-containing carboxylate emulsifier. The purity of the fluorine-containing carboxylic acid prepared by the method can reach 98% or above.
