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37714-64-0

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37714-64-0 Usage

General Description

3-Morpholin-4-yl-3-oxo-propionic acid ethyl ester is a chemical compound with the molecular formula C10H17NO4. It is an ethyl ester derivative of 3-morpholin-4-yl-3-oxo-propionic acid, which is an important intermediate in the production of pharmaceuticals and agrochemicals. 3-Morpholin-4-yl-3-oxo-propionic acid ethyl ester is commonly used as a reagent in organic synthesis and medicinal chemistry research. It is known for its potential as a building block in the synthesis of various bioactive compounds, and it has been studied for its potential pharmacological properties. Overall, 3-Morpholin-4-yl-3-oxo-propionic acid ethyl ester is a versatile compound with diverse applications in the field of chemical and pharmaceutical industries.

Check Digit Verification of cas no

The CAS Registry Mumber 37714-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,7,1 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 37714-64:
(7*3)+(6*7)+(5*7)+(4*1)+(3*4)+(2*6)+(1*4)=130
130 % 10 = 0
So 37714-64-0 is a valid CAS Registry Number.

37714-64-0Relevant articles and documents

Carbene radicals in cobalt(II)-porphyrin-catalysed carbene carbonylation reactions; A catalytic approach to ketenes

Paul, Nanda D.,Chirila, Andrei,Lu, Hongjian,Zhang, X. Peter,Debruin, Bas

supporting information, p. 12953 - 12958 (2013/10/01)

One-pot radicals: Cobalt(III)-carbene radicals, generated by metallo-radical activation of diazo compounds and N-tosylhydrazone sodium salts with cobalt(II) complexes of porphyrins, readily undergo radical addition to carbon monoxide, allowing the catalytic production of ketenes. These ketenes subsequently react with various amines, alcohols and imines in one-pot tandem transformations to produce differently substituted amides, esters and β-lactams in good isolated yields. Copyright

HETEROCYCLIC COMPOUNDS AND USES THEREOF

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Page/Page column 95, (2012/05/21)

Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.

Nucleophilic substitution accompanying carbon-carbon bond cleavage assisted by a nitro group

Nakaike, Yumi,Taba, Noriko,Itoh, Shinobu,Tobe, Yoshito,Nishiwaki, Nagatoshi,Ariga, Masahiro

experimental part, p. 2413 - 2417 (2009/09/08)

A 2-nitrated 3-oxoester reacted with amines or alcohols to afford unsymmetrical malonic acid derivatives as a result of nucleophilic substitution accompanying C-C bond cleavage. The 2-nitrated 3-oxoester easily formed ammonium salts with amines. When the amine is liberated from the salt under equilibrium, nucleophilic amine and electrophilic keto ester locate close to each other. This intimate pair effect causes a pseudo intramolecular reaction to occur, giving rise to effective substitution under mild conditions.

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