3775-55-1 Usage
General Description
2-AMINO-5-(5-NITRO-2-FURYL)-1,3,4-OXADIAZOLE is a chemical compound with the molecular formula C7H6N4O3. It is a nitrofuran derivative, which is a class of compounds known for their antibacterial and antifungal properties. 2-AMINO-5-(5-NITRO-2-FURYL)-1,3,4-OXADIAZOLE has been found to exhibit antimicrobial activity against a variety of pathogens, making it a potential candidate for the development of new antimicrobial agents. It is also known for its potential use as a synthetic intermediate in organic synthesis. Additionally, it is important to handle this chemical with care as it is a potential mutagen and carcinogen.
Check Digit Verification of cas no
The CAS Registry Mumber 3775-55-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,7 and 5 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3775-55:
(6*3)+(5*7)+(4*7)+(3*5)+(2*5)+(1*5)=111
111 % 10 = 1
So 3775-55-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H4N4O4/c7-6-9-8-5(14-6)3-1-2-4(13-3)10(11)12/h1-2H,(H2,7,9)
3775-55-1Relevant articles and documents
Trypanosoma cruzi: Effect and mode of action of nitroimidazole and nitrofuran derivatives
Maya, Juan Diego,Bollo, Soledad,Nunez-Vergara, Luis J.,Squella, Juan A.,Repetto, Yolanda,Morello, Antonio,Perie, Jacques,Chauviere, Gerard
, p. 999 - 1006 (2007/10/03)
With the aim of determining the actual target(s) of nitro-group bearing compounds considered as possible leads for the development of drugs against Chagas' disease, we studied in parallel nitrofurans and nitroimidazoles. We investigated nine representative compounds for the following properties: efficacy on different Trypanosoma cruzi strains, redox cyclers, inhibition of respiration, production of corresponding nitroso derivatives and intracellular thiol scavengers. Our results indicate that nifurtimox and related compounds act as redox cyclers, whereas the most active in the series, the 5-nitroimidazole megazol essentially acts as thiol scavenger particularly for trypanothione, the cofactor for trypanothione reductase, an essential enzyme in the detoxification process.
