37772-89-7

Basic information

• Product Name: 2,4-Pyrrolidinedione
• Synonyms: 2,4-Pyrrolidinedione
• CAS NO: 37772-89-7
• Molecular Formula: C₄H₅NO₂
• Molecular Weight: 99.09
• Product Categories: Drug Intermediates
• Mol File: 37772-89-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 380.9 °C at 760 mmHg
• Flash Point: 211.3 °C
• Appearance: /
• Density: 1.274 g/cm³
• Storage Temp.: 2-8°C
• PKA: 12.79±0.20(Predicted)
• CAS DataBase Reference: 2,4-Pyrrolidinedione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Pyrrolidinedione(37772-89-7)
• EPA Substance Registry System: 2,4-Pyrrolidinedione(37772-89-7)

Safety Data

• Hazardous Substances Data: 37772-89-7(Hazardous Substances Data)

Usage

General Description

2,4-Pyrrolidinedione, also known as Succinimide, is a chemical compound derived from pyrrolidine, an organic compound. It is an important intermediate in organic synthesis and an enhancer in petroleum products. This white crystalline organic compound is slightly soluble in water and has a molar mass of 99.10 g/mol. Its systematic IUPAC name is pyrrolidine-2,4-dione and it has a planar amide group ring. It's sparingly soluble in cold water and soluble in hot water and alcohol. 2,4-Pyrrolidinedione displays different reactivity due to the acidic hydrogen atom. It's used in various applications, including pharmaceuticals, agricultural chemicals, electronics materials, and even as a beverage additive.

Upstream product

• 114473-74-4 6-Aminomethyl-2,2-dimethyl-[1,3]dioxin-4-one 
• 51925-57-6 methyl 2,4-dioxo-3-pyrrolidinecarboxylate 
• 37772-85-3 methyl 4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate 
• 123-91-1 1,4-dioxane 
• 113896-95-0 4-benzyloxy-1,5-dihydropyrrol-2-one 
• 13679-70-4 5-methylthiophene-2-carboxaldehyde 
• 91502-29-3 4-ethoxy-3-pyrrolin-2-one 

Downstream Products

• 137987-33-8 4-(phenylamino)-1H-pyrrol-2(5H)-one 
• 114343-97-4 2-(1-Propyl-2-oxo-3-pyrrolin-4-yl)amino-3-methylbenzonitrile 
• 433731-24-9 4-((1R,2R)-(2-aminocyclohexyl)amino)-3-pyrrolin-2-one 
• 1613293-50-7 C₂₃H₂₀ClFN₄O₄ 
• 1265206-07-2 5-oxo-2,5-dihydro-1H-pyrrol-3-yl cyclohexanecarboxylate 
• 1265206-05-0 4-(benzoyloxy)-2,5-dihydropyrrol-2(1H)-one 
• 12656-40-5 Althiomycin 
• 137987-35-0 4-(2-aminophenyl)aminopyrroline-2-one 
• 69778-83-2 4-methoxy-3-pyrrolin-2-one 
• 92233-25-5 2-Methoxy-2-pyrrolin-4-one 
• 137987-34-9 4-phenylhydrazinoaminopyrroline-2-one 

Relevant articles and documents

A new amide compounds

The invention provides a novel compound (as shown in the formula I) and salt thereof. Experimental results show that the novel compound can be applied to treating and preventing cerebral ischemic diseases and improving sleep; the novel amide compound can generate salt with alkali metal sodium, magnesium, kalium, calcium, organic base tris, diethyl amine, triethylamine and the like and has the functions of treating and preventing ischemic cardiovascular and cerebrovascular diseases and improving sleep.

REMEDY FOR DIABETES

A method of screening a compound having a hypoglycemic effect (hereinafter referred to as "hypoglycemic compound"), a remedy for diabetes which contains a compound having a novel function mechanism, etc. More specifically speaking, a method of screening a hypoglycemic compound capable of binding to the β subunit of a trimeric GTP-binding protein, a remedy for diabetes comprising a hypoglycemic compound, which is characterized by being capable of binding to the β subunit of a trimeric GTP-binding protein, as the active ingredient, etc.

LACTAM COMPOUNDS AND MEDICINAL USE THEREOF

An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.