37785-48-1

Basic information

• Product Name: 2-(3,4,5-TRIMETHOXYPHENYL)ETHANOL
• Synonyms: 2-(3,4,5-TRIMETHOXYPHENYL)ETHANOL;3,4,5-Trimethoxyphenylethanol
• CAS NO: 37785-48-1
• Molecular Formula: C₁₁H₁₆O₄
• Molecular Weight: 212.24
• Mol File: 37785-48-1.mol
• Article Data: 21

Chemical Properties

• Melting Point: 100℃
• Boiling Point: 179-180 °C(Press: 11 Torr)
• Appearance: /
• Density: 1.106±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.72±0.10(Predicted)
• CAS DataBase Reference: 2-(3,4,5-TRIMETHOXYPHENYL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4,5-TRIMETHOXYPHENYL)ETHANOL(37785-48-1)
• EPA Substance Registry System: 2-(3,4,5-TRIMETHOXYPHENYL)ETHANOL(37785-48-1)

Safety Data

• Hazardous Substances Data: 37785-48-1(Hazardous Substances Data)

Usage

General Description

2-(3,4,5-Trimethoxyphenyl)ethanol, also known as TME, is a chemical compound with the molecular formula C11H16O4. It is a colorless liquid with a floral, woody odor, and is commonly used in the production of perfumes and fragrances. TME is also used as a flavoring ingredient in the food industry, and as a pharmaceutical intermediate in the synthesis of various drugs. It has been found to exhibit antioxidant and anti-inflammatory properties, making it potentially useful in the development of skincare and cosmetic products. Additionally, TME has been studied for its potential anti-cancer and neuroprotective effects, making it an interesting compound for further research and development.

Upstream product

• 13400-02-7 3,4,5-trimethoxy styrene 
• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 13338-63-1 2-(3,4,5-trimethoxyphenyl)acetonitrile 
• 3840-30-0 5-(chloromethyl)-1,2,3-trimethoxybenzene 
• 1916-07-0 3,4,5-trimethoxybenzoic acid methyl ester 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 64-17-5 ethanol 
• 87428-53-3 3,4,5-trimethoxy-α-hydroxyacetophenone 
• 951-82-6 3,4,5-trimethoxyphenyl acetic acid 
• 2989-06-2 methyl 2-(3,4,5-trimethoxyphenyl)acetate 
• 66162-60-5 (3,4,5-trimethoxyphenyl)acetic acid ethyl ester 
• 832-92-8 mescaline hydrochloride 
• 186581-53-3 diazomethane 

Downstream Products

• 62028-45-9 2-(3,4,5-trimethoxyphenyl) ethyl 4-methylbenzenesulfonate 
• 1026105-15-6 2-hydroxy-3,3-diphenyl-3-[2-(3,4,5-trimethoxy-phenyl)-ethoxy]-propionic acid methyl ester 
• 931103-01-4 1,2,3 trimethoxy-5-(prop-2-yn-1-yl)benzene 
• 1219124-84-1 2-(3,4,5-trimethoxyphenyl)ethyl β-D-glucopyranoside 
• 1350703-16-0 2-(3,4,5-trimethoxyphenyl)ethyl β-D-galactopyranoside 
• 910866-99-8 5-(2-azidoethyl)-1,2,3-trimethoxybenzene 
• 54-04-6 mescaline 
• 1616561-64-8 5-(2-(allyloxy)ethyl)-1,2,3-trimethoxybenzene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 204510-65-6 5-(2-iodoethyl)-1,2,3-trimethoxybenzene 
• 40174-10-5 2-(3,4,5-trimethoxyphenyl)ethyl methanesulfonate 
• 85002-65-9 1,2,3-Trimethoxy-5-[2-(4-nitro-phenoxy)-ethyl]-benzene 
• 5320-31-0 3,4,5-trimethoxyphenylacetaldehyde 
• 86106-21-0 5,5-Dimethyl-3-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-thiazolidine-2,4-dione 

Relevant articles and documents

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Iron-Catalyzed β-Alkylation of Alcohols

β-Branched alkylated alcohols have been prepared in good yields using a double-hydrogen autotransfer strategy in the presence of our diaminocyclopentadienone iron tricarbonyl complex Fe1. The alkylation of some 2-arylethanol derivatives was successfully addressed with benzylic alcohols and methanol as alkylating reagents under mild conditions. Deuterium labeling experiments suggested that both alcohols (2-arylethanol and either methanol or benzyl alcohol) served as hydrogen donors in this cascade process.

Highly sulphated cellulose: a versatile, reusable and selective desilylating agent for deprotection of alcoholic TBDMS ethers

A mild, efficient and rapid protocol was developed for the deprotection of alcoholic TBDMS ethers using a recyclable, eco-friendly highly sulphated cellulose sulphate acid catalyst in methanol. This acid catalyst selectively cleaves alcoholic TBDMS ethers in bis-TBDMS ethers containing both alcoholic and phenolic TBDMS ether moieties.