37945-06-5 Usage
Description
[5-chloro-2-[3-(chloromethyl)-4H-1,2,4-triazol-4-yl]phenyl] phenyl ketone is a chemical compound that is synthesized as an impurity during the production of Estazolam (E668380), a benzodiazepine derivative with anxiolytic, anticonvulsant, and muscle relaxant properties.
Uses
Used in Pharmaceutical Industry:
[5-chloro-2-[3-(chloromethyl)-4H-1,2,4-triazol-4-yl]phenyl] phenyl ketone is used as an impurity in the synthesis of Estazolam, a benzodiazepine derivative, for its anxiolytic, anticonvulsant, and muscle relaxant properties. It is commonly prescribed to treat short-term insomnia.
Check Digit Verification of cas no
The CAS Registry Mumber 37945-06-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,9,4 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 37945-06:
(7*3)+(6*7)+(5*9)+(4*4)+(3*5)+(2*0)+(1*6)=145
145 % 10 = 5
So 37945-06-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H11Cl2N3O/c17-9-15-20-19-10-21(15)14-7-6-12(18)8-13(14)16(22)11-4-2-1-3-5-11/h1-8,10H,9H2
37945-06-5Relevant articles and documents
Methods for the production of 4H-s-triazolo[4,3-a][1,4]benzodiazepine 5N-oxides
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, (2008/06/13)
The title compounds are prepared by reacting a 3-amino-3,4-dihydro-4-hydroxy-4-phenylquinazoline with a reactive derivative of a halogenoacetic acid, reacting the resultant halogenoacetyl derivative with a weak acid, reacting the resultant 2-(3-halomethyl-s-triazol-4-yl)benzophenone with hydroxylamine and subjecting the resultant 2-(3-hydroxyamino-methyl-s-triazol-4-yl)benzophenone to dehydration to effect ring closure.
