380380-55-2 Usage
Description
2-OXAZOLIDINONE, 3-(3-FLUOROPHENYL)-5-[[(METHYLSULFONYL)OXY]METHYL]-, (5R)is a chiral compound belonging to the oxazolidinone class of antibiotics, characterized by its molecular formula C13H15FNO5S. 2-OXAZOLIDINONE, 3-(3-FLUOROPHENYL)-5-[[(METHYLSULFONYL)OXY]METHYL]-, (5R)features a fluorophenyl group and a methylsulfonyl group, both contributing to its antimicrobial properties. As a chiral molecule, it exists in two enantiomeric forms, with the (5R)-enantiomer possessing distinct biological interactions and activity, which is significant for the development of novel antibiotics.
Uses
Used in Pharmaceutical Industry:
2-OXAZOLIDINONE, 3-(3-FLUOROPHENYL)-5-[[(METHYLSULFONYL)OXY]METHYL]-, (5R)is utilized as an active pharmaceutical ingredient for the development of medications aimed at treating bacterial infections. Its unique structure and chirality allow for specific biological interactions, making it a valuable component in the creation of new antibiotics to combat various bacterial pathogens.
Check Digit Verification of cas no
The CAS Registry Mumber 380380-55-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,0,3,8 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 380380-55:
(8*3)+(7*8)+(6*0)+(5*3)+(4*8)+(3*0)+(2*5)+(1*5)=142
142 % 10 = 2
So 380380-55-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H12FNO5S/c1-19(15,16)17-7-10-6-13(11(14)18-10)9-4-2-3-8(12)5-9/h2-5,10H,6-7H2,1H3/t10-/m1/s1
380380-55-2Relevant articles and documents
Synthesis and in vitro activity of novel 1,2,4-triazolo[4,3-a]pyrimidine oxazolidinone antibacterial agents. Part II
Khera, Manoj Kumar,Cliffe, Ian A.,Prakash, Om
scheme or table, p. 5266 - 5269 (2011/10/02)
The synthesis and antibacterial activity of 1,2,4-triazolo[4,3-a]pyrimidine oxazolidinones is reported. Compound 3e with a 2,4-disubstituted thiophene ring was found to be a potent inhibitor of Gram-positive pathogens and was 4-16-fold more potent than Linezolid.