380886-38-4

Basic information

• Product Name: Butanoic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-3-methyl-, 1,1-dimethylethyl ester, (2R)-
• Synonyms: Butanoic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-3-methyl-, 1,1-dimethylethyl ester, (2R)-;JSUWPTFAHGCIFF-CYBMUJFWSA-N
• CAS NO: 380886-38-4
• Molecular Formula: C₁₇H₂₁NO₅
• Molecular Weight: 319.35
• Mol File: 380886-38-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 416.922°C at 760 mmHg
• Flash Point: 205.947°C
• Appearance: /
• Density: 1.217g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: Butanoic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-3-methyl-, 1,1-dimethylethyl ester, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-3-methyl-, 1,1-dimethylethyl ester, (2R)-(380886-38-4)
• EPA Substance Registry System: Butanoic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-3-methyl-, 1,1-dimethylethyl ester, (2R)-(380886-38-4)

Safety Data

• Hazardous Substances Data: 380886-38-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H21NO5/c1-10(2)13(16(21)22-17(3,4)5)23-18-14(19)11-8-6-7-9-12(11)15(18)20/h6-10,13H,1-5H3/t13-/m1/s1

Upstream product

• 18667-97-5 (S)-2-acetoxy-3-methylbutanoic acid 
• 380886-48-6 tert-butyl (S)-2-acetoxy-3-methylbutanoate 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 72-18-4 L-valine 
• 524-38-9 N-hydroxyphthalimide 
• 3519-30-0 L-α-hydroxyisovaleric acid t-butyl ester 

Downstream Products

• 310404-44-5 (R)-3-methyl-2-phthalimidooxybutanoic acid 
• 380886-43-1 D-tert-butyl 2-p-chlorophenylcarbonyl-aminoxy-3-methylbutanoate 

Relevant articles and documents

Synthesis and characterization of chiral N-O turns induced by α-aminoxy acids

Chiral α-aminoxy acids of various side chains were synthesized with high optical purity starting from chiral α-amino acids. The conformations of diamides 13a-e, 15, and 16 were probed by using NMR, FT-IR, and CD spectroscopic methods as well as X-ray crystallography. The right-handed turns with eight-membered-ring intramolecular hydrogen bonds between adjacent residues (called the N-O turns) were found to be preferred for D-aminoxy acid residues, and they were independent of the side chains. The rigid chiral N-O turns should have great potential in molecular design.