381248-04-0

Basic information

• Product Name: 2-Chloro-3-pyridylboronic acid
• Synonyms: AKOS BRN-0504;2-CHLORO-3-PYRIDINYL-BORONIC ACID;2-CHLORO-3-PYRIDINEBORONIC ACID;2-CHLORO-3-PYRIDYL BORONIC ACID;2-CHLOROPYRIDINE-3-BORONIC ACID;2-CHLOROPYRIDIN-3-YLBORONIC ACID;3-Chlorpyridine-3-boronic acid;2-Chloro-5-Trimethoxyphenylboronic acid
• CAS NO: 381248-04-0
• Molecular Formula: C₅H₅BClNO₂
• Molecular Weight: 157.36
• EINECS: 1533716-785-6
• Product Categories: BORONICACID;blocks;BoronicAcids;Pyridines;Pyridine;Boronic Acids & Esters;Boronic acid;Organoborons;Boronic Acids & Esters;Boronic Acids;Boronic Acids and Derivatives;Heteroaryl;Boric acid series;pyridine series;Boronate Ester;Potassium Trifluoroborate
• Mol File: 381248-04-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 160°C
• Boiling Point: 349.3 °C at 760 mmHg
• Flash Point: 165.1 °C
• Appearance: White/Crystalline Powder
• Density: 1.41 g/cm³
• Vapor Pressure: 1.78E-05mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: Keep Cold
• Solubility: soluble in Methanol
• PKA: 6.59±0.58(Predicted)
• BRN: 9119913
• CAS DataBase Reference: 2-Chloro-3-pyridylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-3-pyridylboronic acid(381248-04-0)
• EPA Substance Registry System: 2-Chloro-3-pyridylboronic acid(381248-04-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39-24/25-22
• RIDADR: 2811
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 381248-04-0(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

Reactant for:Synthesis of Et canthinone-3-carboxylates from Et 4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-catalyzed Suzuki-Miyaura coupling and a Cu-catalyzed amidation reactionPreparation of arylmethylpyrrolidinylmethanols and amine derivatives via reaction with MIDA followed by Suzuki reaction with halides or amination with aminesPreparation of arylazabicyclooctane derivatives as potential arginine vasopressin receptor antagonistsRegioselective preparation of halo-oligopyridines and oligopyridines by the Suzuki-Miyaura cross-coupling reaction

InChI:InChI=1/C5H5BClNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3,9-10H

Downstream Products

• 943152-52-1 (R)-{1-[4-(2-chloro-pyridin-3-yl)-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 1025751-74-9 3-(1-benzyl-1H-pyrazol-4-yl)-2-chloro-pyridine 
• 1055307-69-1 C₁₆H₁₁ClN₂O₃S 
• 942206-19-1 2,6'-dichloro-3,3'-bipyridine 
• 1426414-42-7 (S)-1-(2-chloropyridin-3-yl)-1-phenylethanol 
• 1426414-53-0 (R)-2-chloro-3-(1-phenylethyl)pyridine 
• 1426414-39-2 (R)-2-chloro-3-(1-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl)pyridine 
• 452972-11-1 2-[(2-chloro)pyridin-3-yl]-4,4',5,5'-tetramethyl-1,3-dioxaborolane