38150-27-5

Basic information

• Product Name: 5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone
• Synonyms: 5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone;HB-compound;5-CHLOOR-2-[3-(HYDROXYMETHYL)-5-METHYL-4H-1,2,4-TRIAZOOL-4-YL]BENZOFENON;[5-Chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]phenyl]phenyl ketone;2-[3-(Hydroxymethyl)-5-methyl-4-triazolyl]-5-chlorobenzophenone;Alprazolam EP Impurity B
• CAS NO: 38150-27-5
• Molecular Formula: C₁₇H₁₄ClN₃O₂
• Molecular Weight: 327.76496
• EINECS: 253-805-6
• Product Categories: Amines;Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 38150-27-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 118-120°C
• Boiling Point: 593.7°Cat760mmHg
• Flash Point: 312.8°C
• Appearance: /
• Density: 1.34g/cm³
• Vapor Pressure: 6.11E-15mmHg at 25°C
• Refractive Index: 1.654
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone(38150-27-5)
• EPA Substance Registry System: 5-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone(38150-27-5)

Safety Data

• Hazardous Substances Data: 38150-27-5(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

InChI:InChI=1/C17H14ClN3O2/c1-11-19-20-16(10-22)21(11)15-8-7-13(18)9-14(15)17(23)12-5-3-2-4-6-12/h2-9,22H,10H2,1H3

Upstream product

• 36916-19-5 5-chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone 

Downstream Products

• 38150-33-3 5-chloro-2-[3-(dimethylamino-methyl)-5-methyl-[1,2,4]triazol-4-yl]-benzophenone 
• 38150-28-6 2-(3-bromomethyl-5-methyl-[1,2,4]triazol-4-yl)-5-chloro-benzophenone 
• 37945-07-6 5-chloro-2-(3-chloromethyl-5-methyl-[1,2,4]triazol-4-yl)-benzophenone 
• 54196-63-3 N-<<4-(2-Benzoyl-4-chlorophenyl)-5-methyl-4H-1,2,4-triazol-3-yl>-methyl>phthalimide 
• 40545-72-0 5-chloro-2-(3-methyl-5-pyrrolidin-1-ylmethyl-[1,2,4]triazol-4-yl)-benzophenone 
• 61955-42-8 N-<<4-(2-Benzoyl-4-chlorophenyl)-5-<2-(dimethylamino)ethyl>-4H-1,2,4-triazol-3-yl>methyl>phthalimide 
• 60218-33-9 8-chloro-1-<2-(dimethylamino)ethyl>-6-phenyl-4H-s-triazolo<4,3-a><1,4>benzodiazepine p-toluenesulfonate 
• 28981-97-7 alprazolam 
• 61955-41-7 2-<3-(hydroxymethyl)-5-(2-dimethylamino)ethyl>-4H-1,2,4-triazol-4-yl-5-chloro-benzophenone 
• 121899-18-1 {5-Chloro-2-[3-(1-dimethylaminomethyl-vinyl)-5-hydroxymethyl-[1,2,4]triazol-4-yl]-phenyl}-phenyl-methanone 

Relevant articles and documents

2-[3-(Phthalimidomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenones

A process to make 6-phenyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepines by converting 2-[3-(hydroxymethyl)-4H-1,2,4-triazol-4-yl]benzophenones to 2-[3-[(phthalimido or methanesulfonyl)methyl]-4H-1,2,4-triazol-4-yl]benzophenones and converting these compounds to the highly active 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines useful as tranquilizers and sedatives.