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38402-02-7

38402-02-7

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38402-02-7 Usage

Chemical Properties

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Check Digit Verification of cas no

The CAS Registry Mumber 38402-02-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,4,0 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 38402-02:
(7*3)+(6*8)+(5*4)+(4*0)+(3*2)+(2*0)+(1*2)=97
97 % 10 = 7
So 38402-02-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H16NO2/c1-7(2,3-5-8)4-6-9/h8-9H,3-6H2,1-2H3/q+1

38402-02-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name BIS(2-HYDROXYETHYL)DIMETHYLAMMONIUM CHLORIDE

1.2 Other means of identification

Product number -
Other names EthanaMiniuM,2-hydroxy-N-(2-hydroxyethyl)-N,N-diMethyl-,chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:38402-02-7 SDS

38402-02-7Relevant articles and documents

Improvement of New Dianionic Ionic Liquids vs Monoanionic in Solubility of Poorly Water-Soluble Drugs

Agostinho, Daniela A.S.,Jesus, Ana R.,Silva, Ana B.P.,Esperan?a, José M.S.S.,Paiva, Alexandre,Duarte, Ana R.C.,Reis, Patrícia M.

, p. 2489 - 2500 (2021)

New ionic liquids (ILs) based on dianionic phosphonate anions and ammonium cations were prepared and characterized. They were used as excipients to increase the water solubility of two oral drugs, piroxicam and ibuprofen, that are slightly soluble in water. An increment in solubility of 300-fold was achieved for ibuprofen when compared with pure water, with only 0.25 mol% of IL in water. Interestingly, this was achieved with the less toxic dianionic ionic liquid [N4 1 2OH 2OH]2 [C2H5PO3], which presents an IC50 of 120 mM (≈0.25 mol%). On the other hand, piroxicam showed an increase of 480-fold for the same dianionic ionic liquid, with the same ionic liquid percentage. In contrast, for monoanionic ionic liquids, the effect was not so pronounced, and only a 10-fold was obtained, in the presence of 0.3 mol% of IL. The lipophilicity (logP) of drugs decreased in the presence of these ILs. Cytotoxicity profile of these ILs was determined and they did not show a significant impact towards healthy fibroblasts. The cytotoxicity of ibuprofen and piroxicam was also determined, and cellular viability almost did not change when ionic liquid was in the presence of 1 mM of oral drug.

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