38459-64-2Relevant articles and documents
Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C
Carpenter, Colleen,Sorenson, Roderick J.,Jin, Yafei,Klossowski, Szymon,Cierpicki, Tomasz,Gnegy, Margaret,Showalter, Hollis D.
, p. 5495 - 5504 (2016)
The clinical selective estrogen receptor modulator tamoxifen is also a modest inhibitor of protein kinase C, a target implicated in several untreatable brain diseases such as amphetamine abuse. This inhibition and tamoxifen's ability to cross the blood br
A one-pot multicomponent ‘click’ approach to the synthesis of novel tamoxifen-triazole conjugates using nano iron oxide catalyst and their preliminary antiproliferative activity studies
Katiki, Mohana Rao,Kommula, Dileep,Polepalli, Sowjanya,Jain, Nishant,Murty, Madugula Sree Rama
, p. 846 - 860 (2019/10/28)
Background: In an effort to establish new drug candidates with improved antiproliferative activity, we report here a novel class of compounds designed rationally by the replacement of an ethyl group in tamoxifen with a methylene (1H-1,2,4-triazole) and th
Conjugated polyelectrolytes with aggregation-enhanced emission characteristics: Synthesis and their biological applications
Hu, Rongrong,Ye, Ruquan,Lam, Jacky W.Y.,Li, Min,Leung, Chris W.T.,Tang, Ben Zhong
, p. 2436 - 2445 (2013/10/08)
Conjugated polyelectrolytes are promising candidates for the construction of fluorescent bioprobes. In this study, a series of water-soluble fluorescent polyelectrolytes have been designed and synthesized by means of the quaternization of their tetrapheny
