385-00-2Relevant articles and documents
Nanosheet-assembled microflower-like coordination polymers by surfactant-assisted assembly with enhanced catalytic activity
Han, Suzhen,Hu, Mingjun,Huang, Chao,Lu, Guizhen,Mi, Liwei,Qin, Na,Zhang, Ying-Ying,Zhu, Kaifang
, p. 7858 - 7863 (2020/12/04)
Tuning the morphology and size of coordination polymers (CPs) is an effective strategy to enable crystalline materials for desired applications. Herein, two CPs, named [Cd2(DBTP)(H2O)2]n (1) and {[Zn2(DBTP)(H2O)]·2.5H2O}n (2), were prepared by employing a rigid V-shaped and multidentate N-heterocyclic ligand 2,6-di(1H,2′H-[3,3′-bi(1,2,4-triazol)]-5′-yl)pyridine (H4DBTP) under solvothermal conditions. Their crystal morphologies and sizes were controlled by varying the type and the amount of surfactants. The morphology can be changed from bulk blocks to microflower-like hierarchical spheres assembled by nanosheets and the mean size of the microflowers is approximately 2 μm. Nanoscale 1a and 2a were further evaluated as heterogeneous catalysts for the conversion reactions of nitromethylbenzenes into benzoic acids. The results showed that nanoscale 2a is a more efficient catalyst than nanoscale 1a and their corresponding bulk counterparts.
A biocatalytic method for the chemoselective aerobic oxidation of aldehydes to carboxylic acids
Knaus, Tanja,Tseliou, Vasilis,Humphreys, Luke D.,Scrutton, Nigel S.,Mutti, Francesco G.
supporting information, p. 3931 - 3943 (2018/09/11)
Herein, we present a study on the oxidation of aldehydes to carboxylic acids using three recombinant aldehyde dehydrogenases (ALDHs). The ALDHs were used in purified form with a nicotinamide oxidase (NOx), which recycles the catalytic NAD+ at the expense of dioxygen (air at atmospheric pressure). The reaction was studied also with lyophilised whole cell as well as resting cell biocatalysts for more convenient practical application. The optimised biocatalytic oxidation runs in phosphate buffer at pH 8.5 and at 40 °C. From a set of sixty-one aliphatic, aryl-Aliphatic, benzylic, hetero-Aromatic and bicyclic aldehydes, fifty were converted with elevated yield (up to >99%). The exceptions were a few ortho-substituted benzaldehydes, bicyclic heteroaromatic aldehydes and 2-phenylpropanal. In all cases, the expected carboxylic acid was shown to be the only product (>99% chemoselectivity). Other oxidisable functionalities within the same molecule (e.g. hydroxyl, alkene, and heteroaromatic nitrogen or sulphur atoms) remained untouched. The reaction was scaled for the oxidation of 5-(hydroxymethyl)furfural (2 g), a bio-based starting material, to afford 5-(hydroxymethyl)furoic acid in 61% isolated yield. The new biocatalytic method avoids the use of toxic or unsafe oxidants, strong acids or bases, or undesired solvents. It shows applicability across a wide range of substrates, and retains perfect chemoselectivity. Alternative oxidisable groups were not converted, and other classical side-reactions (e.g. halogenation of unsaturated functionalities, Dakin-Type oxidation) did not occur. In comparison to other established enzymatic methods such as the use of oxidases (where the concomitant oxidation of alcohols and aldehydes is common), ALDHs offer greatly improved selectivity.
A fluorine-containing tetrazine pyridine compound and its use
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Paragraph 0013-0014; 0033; 0034, (2017/08/25)
The invention provides fluorine-containing tetrazine pyridine compounds disclosed as Formula I. The compounds have ultrahigh inhibiting and killing actions on harmful acarids and acarid ova, and can be used as an acaricide for controlling acarid harm in agriculture and forestry.
