38637-88-6Relevant articles and documents
Efficient Synthesis of (±)-Juglomycin A
Min, Jong-Pil,Kim, Ju-Cheun,Park, Oee-Sook
, p. 383 - 390 (2004)
(±)-Juglomycin A has been synthesized in 8 steps from 1-hydroxy-5-methoxynaphthalene.
The Absolute Configuration of the Juglomycins
Krupa, Johann,Lackner, Helmut,Jones, Peter G.,Schmidt-Baese, Karen,Sheldrick, George M.
, p. 345 - 352 (2007/10/02)
The absolute configurations of the known juglomycins A (1) and B (2) have been elucidated by single crystal X-ray structure analysis of 1 and its 6,8-dibromo derivative (1b).The structure of 2 has been corrected; it differs from 1 in its configuration at C-4', and not at C-3' as previously assumed.Relationships with the closely related isochromanquinone antibiotics are discussed. - Keywords: Antibiotics, Juglomycins, Absolute Configuration, NMR Data, Derivatives
The Synthesis of (+/-)-Juglomycin A and (+/-)-Juglomycin B, Racemates of two Isomeric Naturally Occurring Naphthoquinonoid Antibiotics
Giles, Robin G. F.,Mitchell, Peter R. K.,Roos, Gregory H. P.,Struempfer, Jacobus M. M.
, p. 2091 - 2095 (2007/10/02)
Syntheses of diastereoisomeric 5-hydroxy-2-(4'-hydroxy-γ-butyrolacton-5'-yl)-1,4-naphthoquinones (1) and (2) and their 5-deoxy-analogues (3) and (4) are described.The stereochemistries of the latter, being defined through unambiguous synthesis, permit the assignment of the configurations of (1) and (2) (which were obtained from a single precursor) and also those of the natural products, juglomycins A and B.